THE EFFECT OF EXCITATION ON NERVE PERMEABILITY 



455 



outflowing blood was macroscopically free from blood coipuscilos the sciatic 

 nerves on both sides were carefully dissected out and worl^od up. 



Results 



Phosphate Permeability 



In Tabk^ 1 are given the weights ol' tlie IVesh and dry nerve, the per- 

 centage of dry substance, the total phosphorus content of the nerve, 

 the phosphorus content per gm fresh weight, the ratio of the activity 

 per gm dry stimulated and non-stimulated sciatic nerv(>, the ratio of 



Table 1. — Weight of Cat 2.4 kgm Left Nerve Stimulated for (5 Min. At the 

 End of the Fir,st Minute 0.7.5 Millict'RIE ^^p Injected Intravenoitsly. 



Inorganic Plasma P = 6.10 MGM p. c. 



Table 2. — Weight of Cat 2.95 kgm. Left Nerve Stimulated for 5 Min. At the 

 End of the Second Minute 0.3 Millicurie 32p Injected Intravenously. 



Inorganic Plasma P = 4.42 mgm p. c. 



the activites of 1 figm phosphorus extracted from the stimulated and non- 

 stimulated nerve and finally the percentage activity of 1 /<gm total nerve 

 phosphorus relative to that of 1 //gm inorganic phosphorus. 



It will be seen from figures in Tables 1 to 4 that the irritated nerve 

 in each case took up more ^-P than the non-irritated nerve, t h(> ratio 



