Originally puhlisliod in Kql. Dduskc Vidohfkdhcrncfi Sel-flx(th. Jiiologuske 



Mcddelclficr. 14, 5 (1939) 



49. INTERACTION OF PLASMA PHOSPHATE 

 WITH THE PHOSPHORUS COMPOUNDS PRESENT 



IN THE CORPUSCLES 



G. Hevesy and A. H. W. Aten jr. 



From the Instituto for Theoretical Physics, University of Copenhagen 



LIST OF SYMBOLS 



p — total amount of plasma -phosphate; 



c — total amount of acid-soluble phosphorus in corpuscles 



Sp — specific activity of plasma phosphate (activity per mgm phosphorus); 



s^ — specific activity of inorganic phosphorus in corpuscles; 



s^ — average specific activity- of total acid-soluble phosphorus in corpuscles; 



ap — total activity in plasma phosphate; 



a^; — total activity of acid-soluble phosphorus in corpuscles; 



Sp — value of s „ at the end of an experiment ; 



Sj — value of s, at the end of an experiment ; 



Sg — specific activity of acid-soluble organic phosphorus in corpuscles at the 



end of the experiment; 

 S(, — value of s^ at the end of an experiment, etc.; 

 At — total activity of plasma ester at the time; 

 Aq — total activity of plasma ester at the start of the experiment; 

 a — coefficient of penetration; 

 k — rate-constant of the monomolecular decomposition of hexosephosphate in 



blood. 



The distribution of inorganic phosphate and of inorganic acid-soluble 

 phosphorus compounds between plasma and corpuscles deviates from 

 equipartition. This difference in the distribution of the phosphate ion 

 could be due to the fact that during the life time of the corpuscles equi- 

 librium between its contents and those of the surrounding plasma is not 

 yet reached, but it is more probable that we are faced with a case in 

 which the partition coefficient of the ion in question between corpuscles 

 and plasma actually differs from unity. 



The distribution coefficient of inorganic phosphate and also that of 

 the acid-soluble organic phosphorus compounds between plasma and 



