RATE OF. PENETRATION Ol IONS IXTO ERVTIIIIOCYTES 



507 



Table 11. — Distribution of Phosphate Addei> 

 TO THE Blood between Plasma and Corpuscles 



riment, is given by the percentage ^sp found at the end of the experiment 

 in the corpuscles. By subtracting from this figure (35 per cent) the per- 

 centage of plasma P which accumulated in the corpuscles we arrive at 

 the percentage of plasma P which reached the corpuscles solely by inter- 

 change (replacement). This percentage is found to be 22.5. 



In another experiment, to 17 cc. of rabbit blood 0.3 cc. phosphate 

 buffer containing 3.8 mgm of P per cc. was added. An aliquot of the 

 blood was centrifuged at once, another one was shaken at 37° for 21^ 

 hours. The determination of the plasma phosphate gave the following 

 results. 



Table 12. — Dlstribution of Phosphate Added 



TO the Blood between Plasma and Corpuscles 



OF the Rabbit 



Acid soluble P content o£ the plasma in mgm per cent 



At the start 



2^ hours later 



14.4, ^4.4, 14.i7 



I 



II 

 III 

 IV 



11.7 

 12.0 

 11.8 

 12.6 



Average 14.5 



12.0 



Thus, after increasing the plasma P content from 3.5 mgm per cent 

 to 14.5 mgm per cent, 2.5 mgm per cent P corresponding to 23 per cent 

 of the phosphate added left the plasma and accumulated in the cor- 

 puscles. 



