(Glycolysis) 



11 



CO2, 



•2H 



■*■ CH3COCOOH .^ H,NCHCOOH 



(15) 



-CO: 



+ COj, 

 + 2H 



(H) 



CH3 



L- Alanine 



+ COj 



Pyruvic acid 



I+H^o 

 - CO2 

 -2H 



CH3COOH ^. Fatty acid 



Acetic acid oxidation 



COCOOH 



\ (17) ^ 



CH.COOH 

 Oxalacetic acid 



CHjCOOH 



HOCCOOH 

 I 

 CH2COOH 



Citric acid 



HOCHCOOH 



I 

 CH.COOH 



L-Malic acid 



H2NCHCOOH 



CH.COOH 

 L-Aspartic acid 



+ H2O 



(24) 



- H2O 



CHCOOH 



II 

 CHCOOH 



Fumaric acid 



CHCOOH 



CCOOH 

 I 

 CHjCOOH 



cts-Aconitic acid 

 - HjO (19) |+H,a 



HCOHCOOH 



I 

 HCCOOH 



I 



CH^COOH 



d-Isocitric acid 



+ 2H 



CHjCOOH 



CH2COOH 

 Succinic acid 



H2NCHCOOH 

 CHj 



CH2COOH 



L-Glutan\ic 

 acid 



A 



- HjO 

 + CO2 

 + 2H 

 + H.O' 

 -CO2 

 -2H 



COCOOH 



I 

 CHj 



COCOOH 

 I 

 HCCOOH 

 I 

 CHiCOOH 



Oxalosuccinic acid 



- COa 



Fig. 13-4. 



CHjCOOH 

 alpha-Ketoglutaric acid 



The citric acid cycle and related metabolic reactions. 



331 



