74 REFERENCES 



I may, perhaps, re-emphasize one of the points made by our Chair- 

 man. One of the unsolved problems is whether the methods of detection 

 of mutations in different organisms are really capable of producing 

 estimates that are reasonably comparable. This is quite important in 

 some studies. I have particularly in mind studies on the genetic loads 

 in different populations. This is one of the key problems which genetics 

 faces. Do different organisms produce mutations of comparable kinds? 

 If so, how do the frequencies of these different kinds of mutations com- 

 pare in different organisms? About these matters we know at present 

 next to nothing at all. 



Neel: Thank you, Professor Dobzhansky. You have done what we 

 hoped you would do, with remarkable clarity and brevity. Anything 

 else would be anticlimactic. 



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