119 



The two examples discussed, KI and chlorpromazine, were 

 picked at random. Their strong action on E* and the similarity of 

 concentrations in which these drugs acted on £* /w v/tro and ex- 

 erted their pharmacological activity m vivo encourages an exten- 

 sion of the research to other drugs; this may lead to unexpected 

 results, such as actions on £* where no such were expected. This 

 was the case with morphine, novocaine, and salicylate which were 

 found to quench the phosphorescence of rhodamin strongly in 

 10-^ M. Serpasil, the alkaloid of Ramcolfia which is also invoked 

 in the treatment of schizophrenia was found to be even more ac- 

 tive. It completely quenched the phosphorescence of riboflavine in 

 10~* M and suppressed the yellow phosphorescence of quinidine 

 in 10"^ M concentration, turning the light emission of quinidine 

 from whitish-blue to deep blue. 



