GREGORY PINCUS 



CH, 



I 



c=o 



I 



/\ 



A/ 



Progesterone 



Scheme i 



CH3 



I 

 COH 



/X/X 



/\ 



HO— 



A/ 



Pregnanediol-3a, 20a 



+ ? 



/% 



0=4 



/X 



A/ 



CH2OH 



A/V 



Dcsoxycorticosteronc 



/X 



/\ 



HO 



CH, 



I 

 COH 



I 



Pregnanediol-3a, 20a 



+ 



OH 



I 



/^ 



0= 



A/ 



Testosterone 



HO. 



H 



Androsteronc 



(isoandrostcrone 



in guinea pig) 



H 



Etiocholan-3a-ol-17-one 



+ ? 



OH 



I 



/X/X 



HO 



Estradiol 



O 



II 



/X/X 



OH 

 /^/^-OH 



HO 



> /\ 



Estrone 



HO— 



+ 



Estriol 



312 



