CANCER ANAEMIA 



609 



Comment on paper 60 



In the course of the last two years, the plasma iron turnover of 27 women suffer- 

 ing from cancer of the uterine cervix was determined in our laboratory prior to 

 and about one year after successful radiotherapeutic treatment by Dr. Kottmeier, 

 director of the gynaecological department of Radiumhemmct. With the exception 

 of 2 patients all have shown a significantly decreased iron turnover after treat- 

 ment. The mean value of the iron turnover being prior to treatment 1.22 and 

 after successful treatment 0.75 mgm Fe(hr)l RBC (p < 0.001). The mean haemo- 

 poetic data of all treated patients are seen from the figures stated below. The first 

 column indicates data prior to, the second column such after treatment. The 

 patients were slightly anaemic only and their plasma iron concentration was nor- 

 mal, both before and after treatment. Iron turnover figures and also plasma 

 volume differ significantly prior to and after therapy. All recidivous patients 

 investigated were showing turnover values between 1.07 and 1.32,mgm Fe(hr)/1 RBC 

 A detailed presentation of the results obtained is given by Lockner. 



D. Lockner, Acta Haematol. In 22, 311 (1960). 



Plasma-Vol 



ml /kg 



Blut-Vol . 

 ml / kg 



Fe mg /h 

 I RBC 



-< 



RBC-Vol. 

 ml/kg 



unD«n 



Ben 



20 



a 



1.0 

 08 



M m 



Significant Significant Significant 



difference No difference difference difference 



NDdfferancii Nod.ffertnM Nodifference Nodlfference Nodiffcrencc ^,gn,iicani 



difference 



39 Hevesy 



