630 



ADVENTURES IN RADIOISOTOPE RESEARCH 



As seen in Fig. l,the effect of irradiation with such a high dose as 

 1500 r influences the rate of extrusion of 59Fe from the plasma, when 

 measured 1 hour only after exposure, is much less than an irradiation 

 with 800 r only, when the rate of extrusion is measured 2 days after 

 irradiation. 



-■ 1 r 



120 180 



rime in minutes 



240 



30C 



Fig. 1, Effects of exposure to Eoentgen rays on the rate of extrusion of 

 circulating labelled plasma iron from the circulation of rabbits. 



Table 3. — Incoeporation of Intekperitoneally Injected 

 ^'Fe in the Course of 5 Hours into the Hemoglobin of Con- 

 trols AND With 500 r Irradiated Rabbits. C = Control. 



R = Exposed 



* For the bone marrow hemin the corresponding figure was 43. 

 •* Data obtained by Huff et ai.("> 



When injecting rabbits weighing 600 gm intraperitoneally with labelled 

 FeClg 48 hours after exposure to 500 r, we observed 5 hours after injection 

 the 59Fe content of the plasma to be 120% higher than that of the control. 

 In experiments in which 500 — 900 gm rabbits were injected intraperi- 

 toneally within 1/2 hour after irradiation with 5 jugm labelled iron as 

 FeClg and killed 3 hours later, the ^sFe content of the plasma was increased 

 by 6% only. Further data on the effect of time which elapsed after 



