NUCLEIC ACID IN RETROGRADE SARCOMATA 735 



Activity of 1 mgm desoxyribosenucleic acid P, expressed in percentage 

 of the activity of 1 mgm inorganic P from the 



sarcoma plasma liver 



1.12 1.05 1.28 



Activity of 1 mgm desoxyribosenucleic acid P, expressed in percentage- 

 of the activity of 1 mgm inorganic P from the 



sarcoma P plasma P liver P 

 2.57 1.18 0.94 



Experiment 54: I to III. 



Volumina of the sarcomata are stated in K. Sv. Vet.-Akad. Arkiv f. 

 Kemi A 17 No. 30, 0. 41. 



Activity of 1 mgm desoxyribosenucleic acid P, expressed in percentage 

 of the activity of 1 mgm inorganic P from the 



sarcoma plasma liver 



1.19 1.05 1.03 



In Table 2, data on the mean renewal rate of desoxyribosenucleic acid 

 in 26 sarcomata are given. 



(A) is the mean average for each separate experiment involving 

 several animals. 



(B) is the mean figure, when all the sarcomata are considered col- 

 lectively. 



Table 2 



Activity of 1 mgm desoxyribonucleic acid P of retrograde Jensen sarcomata, expressed 

 in percentage of the activity of 1 mgm inorganic P from the 



In Table 3 we state the ratio of the activity of 1 mgm desoxyribose- 

 nucleic acid P, to that of 1 mgm inorganic P from the sarcoma, the 

 plasma and the liver respectively, as found earlier. 



A comparison of the figures in Tables 2 and 3 leads to the conclusion 

 that there is no pronounced difference between the percentages of 

 newly formed desoxyribosenucleic acid in retrograde and in growing 

 sarcomata; the difference amounting only to 12 per cent when consi- 

 dering the "sarcoma scale", and to 25 per cent when considering the 

 "plasma scale". The significance of these scales is discussed below. 



The autolysis of the tissue, followed by a regression of the sarcoma, 

 leads to a desrease in the total desoxyribosenucleic acid content of 1 he- 



