800 



ADVENTURES IN RADIOISOTOPE RESEARCH 



14000-1 



13000 



12000 - 



11000 



10 000 - 



9000 



8000- 



7000 



6000- 



5000- 



4000 - 



3000 



2000- 



Acetate 



lOOO 



1 1 ~ 1 i 1 I I r 



O 10 20 30 40 50 50 70 80 90 100 

 Time in min. 



Fig. 1. Change in specific activity of the expiratory carbon dioxyde 



following injection to rats of labelled acetate and succinate, 



respectively (Gould et al.)(i) 



the specific activity of the expiratory COg increases in the eourse of the 

 first 20 minutes (in the mouse during a shorter interval), absorption, 

 distribution and metabolism of acetate taking some time. "COg forma- 



(1) R. G. Gould, F. M. Sinex, I. N. Rosenberg, A. K. Solomon and A. E. 

 Hastings, J. Biol. Chem. Ill, 295 (1949). 



