804 



ADVENTURES IN RADIOISOTOPE RESEARCH 



In the liver of mice killed at different intervals after injecting labelled 

 acetate, an acceleration of the rate of conversion of acetate into fatty 

 acids can be expected to lead in the first minutes to an increased i*C 

 content of the fatty acids. However, when a maximum activity is reached 

 (cf. right part of the curves in Fig. 3), due to the now increased rate of 

 disappearance of the administered labelled acetate with time a more 



150- 



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Q. 



I- 

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100 



50- 



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^ — ^ ^°^s 



mm. 



Fig. 3. Change of the l*C content of liver fats, Hver total tissue and 

 liver proteins of mice injected with NaCHg "CO^ with time. Each 

 point represents the value obtained for 10 or more pooled livers. 

 Values obtained for mice of different ages and races were plotted 

 solely to demonstrate the great difference in the change of the ^^C 

 content of liver fats and liver proteins with time. 



