1008 



ADVENTURES IN RADIOISOTOPE RESEARCH 



Intervals and the activity of 20 mg haemin isolated from the red cor- 

 puscles compared. His results are seen in Fig. 9. The cancerous environ- 

 ment shortened the life-cycle of the erythrocytes of the mouse from 40 



30- 



o 



XI 



U 



CO 



£ 20 



u 



£10- 



o 



I 



I 2 3 stage of cancer 



° Non cancer 



o 



Cancer 



I 1 



0,5 1,0 



Iron turnover in plasma (mg/kg/day) 



Fig. 8. — Loss of ^^Cr by the in vitro labelled and reinjected red 

 corpuscles in the circulation of normals and of such with cervix 



uterine cancer. 



Cancer 

 inoculated 



28- 



24- 



20- 



■>I6 



«.- 

 o 

 o 



^ 12 



CJ 



a. 



4- 



0= control 

 X= cancer 



days 



Fig. 9. — Loss of ^*C by the haemin of the red corpuscles of control 

 mice and such inoculated with ascites cancer cells 5 days following 

 injection of glycine-^*C-2. The figure is showing the effect of cancer 

 on red corpuscles formed in the non-cancerous organism. 



