153 



Radiation (cont'd.) 



effects on hemoglobin, 25 

 effects on incorporation of 

 labeled precursors, 121 

 effects on interaction of cellu- 

 lar components, 86 

 effects on metabolism of 

 nucleic acid, 1 19 

 effects on mitochondria, 109 

 effects on molecular clusters, 

 leaks, and environment, 110 

 effects on molecular struc- 

 ture, 126 



effects on molecules in vitro, 

 30 



effects on oxidative phos- 

 phorylation by spleen, 99 

 effects on protein, 9, 34 

 effects on respiration, 102 

 effects on respiration of 

 bacteria, 103 

 effects on respiration of 

 E. coli, 54 



effects on respiration of sea 

 urchin eggs and sperm, 103 

 effects on serum lipoprotein 

 metabolism, 93 

 effects on SH groups, 31, 87 

 effects on solubility, 8 

 effects on thymus compared 

 with HN2> 96 

 effects on transforming 

 principle, 126 

 effects on virus, 21 

 enhancement of action, 40 

 immediate effects on respi- 

 ration of bone marrow, 103 

 inactivation of RNA and DNA 

 in yeast, 82 



inactivation of transforming 

 principle, 3 



inactivation volume of dry 

 myosin and ribonuclease, 5 

 induction of lysogeny, 137 

 induction of nucleic acid syn- 

 thesis, 138 



initial chemical effects vs. 

 primary effects, 92 

 initial effects of low doses, 



91 



ionic yield for indirect 

 action, 3 



lethal vs. injurious action, 91 

 migration of energy, 8 

 primary radio-chemical ac- 

 tion on bonds, 1 1 3 



Radiation (cont'd.) 



proportions of direct and in- 

 direct action, 3 

 protection afforded by capture 

 of ionization product, 44 

 protective effects of anoxia, 

 101 



protective effects of cysteine 

 and mercaptoethylamine, 101 

 protective effects of PAPP, 

 100 



reliability of organ weights 

 as a measure of response, 101 

 relation of dose to cross-link- 

 ing in methacrylate, 26 

 relation of molecular size to 

 radiation response, 107 

 response of suballeles and 

 subgenes, 114 



role of purine and pyrimidine 

 in effects on nucleic acid, 122 

 study of structure, 1 



Radicals 



measurement of half-life in 



water, 2, 4, 26 

 Radiobiological action 



diffusion theory, 25 

 Radiobiology 



theoretical approach, 2 

 Radioresistance 



decreased by hypophysectomy, 



NH^, and O^, 104 



molecular dissipation of en- 

 ergy, 20 

 Radiosensitivity 



alteration by pretreatment, 



8 



cellular selection, 104 

 differences in cells of tumor, 



69 



role of solubility, 8 



transforming principle, 4 

 Random walk migration 



electron in polypeptide chain, 



15 

 Respiration 



effects of radiation, 102 

 Respiratory pigments, 30 

 Ribonuclease 



inactivation volume, 5 



relation of molecular length 



to radiation response, 107 

 Ribose nucleic acid 



effects of inactivation on cell 



size, 77 



ionic yield, 38 



