Eupatorium perfoliatum. 135 
The efficaciousness of bone-set is not confined to the simple forms 
of intermittent fever. It has, beyond disputation, been successfully 
employed in remitting bilious, in yellow, and typhus fevers, particu- 
larly in the form of the latter disease, lately so rife throughout the 
United States. And it is in cases of this disease that I have myself 
used it, and in which I can offer the additional experience of an ex- 
cellent practitioner, the late Samuel C. Hopkins, M. D.* This gentle- 
man resided in the village of Woodbury, New Jersey, and enjoyed 
an extensive practice in a range of fifteen or twenty miles of a po- 
pulous tract of country, in which, from the low and marshy nature 
of the soil—exposure of many of the inhabitants holding fisheries, to 
the water, and other pernicious causes—intermittent and typhus 
fevers were very prevalent, and the latter particularly malignant. 
The Doctor was among those partial to the sweating plan of 
treating this fever, and his unusual success in a multitude of 
eases for five or six years in succession, is strongly in favour of that 
mode of practice. The bone-set was the medicine used in produc- 
ing this effect. He prescribed it freely in warm and cold decoction, 
but preferred the warm. He assured me that in many instances, his 
sole reliance was on this plant, which was occasionally so varied in 
its manner of exhibition, as to produce emesis; and frequently was 
intentionally pushed to such extent, as to excite free purging. Its 
* Late of Philadelphia.—This amiable and excellent man fell a victim to typhus 
fever. 
