EUONYMUS ATROPURPUREUS. 
culiar bitterness that is very permanently tonic, and some- 
what anti-periodic. It exhibits also a laxative power, on 
account of which it is esteemed very valuable in the treat- 
ment of dyspeptic complaints, for the stomach will bear this 
substance with advantage while many other tonics produce 
disagreeable symptoms. Some physicians and practitioners 
regard it as one of the most valuable articles in dyspepsia. 
This medicine is also particularly useful in all cases of de- 
bility, and valuable as a tonic after intermittent fever or fever 
and ague. When depended on for the cure of ague, it 
should be preceded by an emetic or cathartic, as the circum- 
stances may require, and then, if freely and perseveringly 
applied, it will generally be successful. It may be used alone, 
or combined with balmony or any other tonic. The dose is 
from half to a whole teaspoonful three or four times a day. 
The seeds of the Spindle-tree, as well as those of the other 
species, are all nauseous, purgative, and emetic, and are used 
in some places to destroy vermin on the hair. The leaves 
are poisonous to sheep and other animals feeding on them. 
Mr. C, A. Santos, of Norfolk, Va., in a dissertation upon 
the subject published in the American Journal of Pharmacy 
(XX. 80), speaks of the bark as tonic, hydragogue, cathartic, 
diuretic, and antiperiodic. Dr. Twyman, of Westport, Mass., 
found it, as a cathartic, rather to resemble rhubarb than to 
possess hydragogue properties, and thought he had obtained 
useful effects from it as an alterative to the hepatic function. 
On the whole, the character of its action may be considered 
as somewhat uncertain, and it might, therefore, well form an 
object of further examination. 
_ The following are the principal preparations of this medi- 
cine : — 
Tinctura Evonymus. ‘Take of the bark in coarse powder 
four ounces, alcohol two pints. Digest seven days and filter. 
Tincture of Euonymus. Tonic and antiperiodic, useful in 
intermittent and remittent fever, and in general debility. 
The dose is from two to four fluid ounces. 
Exrractum Evonymus. Take Euonymus bark four pounds, 
alcohol two and a half gallons, water three gallons. Digest 
in the alcohol at a temperature a little below the boiling 
point for four hours, or keep in a warm place for a week, 
strain through calico, and distil to one pint. Boil the bark in 
the water for four hours over a slow fire, strain and evaporate 
to one pint. Mix the liquors and evaporate by means of a 
water-bath to the proper consistence. | 
Extract of Euonymus. This article is an excellent laxative 
bitter, and is very highly esteemed in convalescence from 
_ fever, especially when of an intermittent or remittent type, 
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