3i6 CLASSICS OF MODERN SCIENCE 

 dogs which had been rendered refractory by preventive inoculations. 

 Thirteen only of them had after their vaccination been already sub- 

 mitted to the test-inoculation on the brain. 



The nineteen dogs were, for the sake of comparison, divided into 

 sets along with nineteen more control dogs brought from the pound 

 without any sort of selection. To begin with, two refractory dogs 

 and two control dogs were on June i trephined and inoculated under 

 the dura-mater, on the surface of the brain, with the bulb of a dog 

 affected with ordinary street rabies. 



On June 3 another refractory dog and another control dog were 

 bitten by a furious street mad dog. 



The same furious mad dog was on June 4 made to bite still another 

 refractory and another control dog. On June 6 the furious dog which 

 had been utilised on June 3 and 4 died. The bulb was taken out and 

 inoculated, after trephining, into three refractory dogs and three con- 

 trol dogs. On June 10 another street mad dog, having been secured, 

 was, by the commission, made to bite one refractory and one control 

 dog. On June 16 the commission had two new dogs, a refractory 

 one and a control one, bitten by one of the control dogs of June i, 

 which had been seized with rabies on June 14 in consequence of the 

 inoculation after trephining which it had received on June i. 



On June 19 the commission got three refractory and three control 

 dogs inoculated before their own eyes in the popliteal vein with the 

 bulb of an ordinary street mad dog. On June 20 they had inoculated 

 in their presence, and still in a vein, ten dogs altogether, six of them 

 refractory and four just brought from the pound. 



On June 28, the Commission hearing that M. Paul Simon, a vet- 

 erinary surgeon, had a furious biting mad dog, had four of their 

 dogs, two refractory and two control dogs, taken to his place and 

 bitten by the mad dog. 



The Rabies Commission have, therefore, experimented on thirty- 

 eight dogs altogether — namely, nineteen refractory dogs and nineteen 

 control dogs susceptible of taking the disease. Those of the dogs 

 which have not died in consequence of the operations themselves are 

 still under observation, and will long continue to be. The commis- 

 sion, reporting up to the present moment on their observations as to 

 the state of the animals tried and tested by them, find that out of the 

 nineteen control dogs six were bitten, of which six three have taken 



