Page 



Field T-3: Category of the Test Compound's Effect, Representing 



Practical Use 169 



Field U: Miscellaneous Time Values: Duration of Response to the Test 

 Compound; Alteration of the Survival Time by the Test Com- 

 pound; Time to Any Response to the Test Compound other than 

 Death; Killing Time of the Test Compound; and Persistence of 

 Activity of a Residue of the Test Compound 17 3 



Field V: Time to Evaluation of the Response to the Test Compound 175 



Field W: Qualification of the Negative and Positive Character of 

 Test Results; Information about Slope of the Dosage 

 Response Curve Present in the Data Source: Introduction 176 



Qualification of a Negative Evaluation in Field Y 177 



Qualification of a Positive Evaluation in Field Y 178 



Fields X and Y: Criteria for Evaluation of Effectiveness (Field X) 



and Evaluation of Effectiveness (Field Y) of the 



Biological Response 181 



Log-Probit Grid 193 



APPENDDCES 195 



Appendix A 



The Biology IBM Punched Card 1 97 



The Biology Code Sheet 199 



Coding of Chemical Structures; the CBCC Chemistry Code, the Chemistry 



IBM Punched Card; the Chemistry Code Sheet; the Chemistry Index Card 200 



CBCC Files 



Code Sheet Files 207 



IBM Punched Card Files 



Biology Punched Card Files 208 



Chemistry Punched Card Files 210 



Miscellaneous Files 211 



Procedures of the CBCC in Collecting and Organizing Information 



Selection of Chemical-Biological Information 211 



Assignment and Coding 212 



Checking and Arbitrating of Coding 213 



Processing of Biology Code Sheets by Chemists 213 



Transfer of Coded Information to IBM Punched Cards 214 



Filing of Biology Code Sheets 214 



Correction of the Files 214 



