FIELDS G-1 and G-2 

 Columns 27 and 28 



physiological stress. {If the test organism has had removed from it an organ for any purpose 

 other than to produce stress, the condition is coded by Symbol P. ) If the organism has an 

 organ or tissue, other than an organ or tissue responding specifically to the test compound 

 (therefore not coded in Field H- 1 or I), which is in a pathological state different from the 

 state of the test organism as a whole, use Symbol and, if it is an organ in this pathological 

 state, code it in Field H-2 (if it is a tissue, it can not be coded in Field I). If, instead of 

 the organism as a whole, an organ or tissue is the structure responding specifically to the test 

 compound and is therefore coded in Field H-1 or I, and it is in a pathological state, use Symbol 

 N or S. 



8 ORGANISM, ORGAN, TISSUE, OR CELL IS IN AN INACTIVE STATE; e. g. , hypnosis, estivation, 



diapause, dormancy, bacterial resting stage, hibernation. 



9 PARABIOTIC 



A PARTHENOGENETIC 



B ORGANISM, ORGAN, TISSUE, OR CELL IS HORMONE DEFICIENT (the deficiency not being the 



condition treated). Symbol B has priority over Symbol P in Field G and is used for any experi- 

 mental hormone deficiency. When an endocrine gland is extirpated to produce the experimental 

 hormone deficiency, code the gland removed or modified in Field H-2. This includes situations 

 in which the hormone deficiency is relative only to the developmental stage of the test organism 

 being treated with the test compound; e. g. , the removal of the endocrine gland and juvenile 

 hormone of larval insect stages. 



C ORGANISM, ORGAN, TISSUE, OR CELL HAS A HORMONE EXCESS (this excess not being the 



condition treated). This includes situations in which the excess is relative only to the develop- 

 mental stage of the test organism being treated with the test compound; e. g. , the application 

 of the juvenile hormone to insect stages in which the hormone is normally virtually absent. 



D ORGANISM, ORGAN, TISSUE, OR CELL IS DEFICIENT IN ONE OR MORE VITAMINS, ONE OR MORE 



MINERALS, ONE OR MORE SPECIFIC NUTRIENTS (E.G. , A SPECffIC AMINO ACID), OR WATER. 

 Symbol D is not used for general deficiency in nourishment- -see Symbol E. Symbol D is used 

 to code incidental dietary deficiencies of normal organisms; it is not a device for indicating 

 that the organism is a special strain or breed which can not synthesize the nutrient or vitamin. 

 Any special strain, such as one dependent on exogenous nutrient or vitamin sources, is 

 indicated by Symbol F. 



E ORGANISM, ORGAN, TISSUE. OR CELL IS UNDERNOURISHED; generally deficient in nutrients; 



fasted; deficient in caloric intake. For the deficiency of a specific essential dietary 

 component, use Symbol D. 



F ORGANISM IS OF A SPECIAL STRAIN: selected, adapted, derived, mutant. (This excludes those 



special strains for which are provided the specific symbols, G, H, and I, below. Neither is 

 Symbol F used to distinguish a taxonomic strain which is either given special designation in 

 the Taxonomy Code of Field E or is not indicated at all by code. ) (See the Key section on 

 Specific Directions and Explanations, Division 9, for the CBCC's exceptional use of Symbol F. ) 



ORGANISM IS OF A STRAIN RESISTANT TO THE TEST COMPOUND . 

 (Use Symbol J for an individual organism, of a non-resistant 

 strain, made resistant by a prior exposure to the test compound. ) 



ORGANISM IS OF A STRAIN SENSITIVE TO THE TEST COMPOUND . 

 (Use Symbol 6 for an individual, of a non-sensitive strain, 

 sensitized to the test compound by prior exposure. ) 



ORGANISM IS OF A STRAIN DEPENDENT ON THE TEST COMPOUND. 



Use Symbol F for strains 

 resistant to, sensitive 

 > to, or dependent on 

 compounds other than 

 the test compound 



ORGANISM IS OF A NON-RESISTANT STRAIN, OR ORGAN, TISSUE, OR CELL IS OF SUCH AN 

 ORGANISM, AND IS MADE RESISTANT TO (L E. , TOLERANT OF) THE TEST COMPOUND. (Use 

 Symbol 6 for the state of sensitization to the test compound. For a resistant strain , use 

 Symbol G. ) 



95 - 



