FIELD T-1 

 Column 57 



L Returns the subject to normal (i. e. , cures the host In Field J) by affecting the pathological 



biological condition or process coded in Field T-2, when restoration of normalcy is not a 

 matter of correcting an abnormally intensified (or speeded) or decreased (or slowed) condition 

 or process. For example, a disturbed nitrogen balance or specific behavior of the host of the 

 disease can not properly be described as being returned to normal by "increasing" or 

 "decreasing" the balance or behavior, but only by restoring its normalcy. Symbol L can also 

 be used when the test compound re-initiates a normal physiological process stopped by the 

 pathology coded in Field E and thereby restores the process to its normal state or rate (i. e. , 

 when a cure is effected). Symbol L implies complete relief from (i. e. , cure of) the pathology 

 symptom (e. g. , balance or behavior) coded in Field T-2; if only improvement but not cure is 

 provided by the test compound or if a pathologically totally suspended process is re-initiated 

 but not restored to the normal state, use Symbol 0. 



M Returns the subject toward normal (i. e. , improves but does not cure the host in Field J) by 



increasing or speeding the pathologically reduced or retarded biological condition or process 

 coded in Field T-2. Symbol M implies only partial relief from the pathological symptom coded 

 in Field T-2; if the test compound cures the host, use Symbol J. 



N Returns the subject toward normal (i. e. , improves but does not cure the host in Field J) by 



decreasing or slowing the pathologically intensified or accelerated biological condition or 

 process coded in Field T-2. Symbol N implies only partial relief from the pathological 

 symptom coded in Field T-2; if the test compound cures the host, use Symbol K. 



Returns the subject toward normal (i. e. , improves but does not cure the host in Field J) by 



affecting the pathological biological condition or process coded in Field T-2, when restoration 

 of normalcy is not a matter of correcting an abnormally increased (or speeded) or decreased 

 (or slowed) condition or process. (See the examples with the definition of Symbol L. ) 

 Symbol is also used when the test compound initiates again a normal physiological process 

 stopped by the pathology coded in Field E but does not thereby restore it to its fully normal 

 state or rate. Symbol implies only partial relief from the pathological symptom (e. g. , 

 balance or behavior) coded in Field T-2; if the host is restored to normalcy or if a pathologically 

 totally suspended process is re-initiated and thereby restored to normalcy, use Symbol L. 



P Exacerbates the subject's pathological state (i. e. , intensifies the pathological condition of 



the host in Field J) by further decreasing or slowing the depressed or slowed biological 

 condition or process coded in Field T-2. 



Exacerbates the subject's pathological state (i. e. , intensifies the pathological condition of 



the host in Field J) by further increasing or speeding the intensified or accelerated biological 

 condition or process coded in Field T-2. 



R Exacerbates the subject's pathological state (i. e. , intensifies the pathological condition of 



the host in Field J) by making further deviant the pathological disbalance or behavior coded 

 in Field T-2 (i. e. , when the exacerbation is not adequately expressed as "increasing" or 

 "decreasing" the pathologically affected condition or process coded in Field T-2). (See the 

 examples with the definition of Symbol L. ) 



Causes no effect. To be used only when the test compound was not tested for a specific action 

 on any specific biological condition or process of Field T-2 and it did not produce any specific 

 action. This symbol is used only with Symbol 1 of Field T-2 which is a symbol for a collective 

 general term, in contrast to all other items of Field T-2 which are specific conditions or 

 processes. Consult the Key. 



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