FIELD T-2 

 Columns 58, 50, 60, and 61 



Enzyme and enzyme action. (See the 

 note below. ) 



Note: If the test compound affects, or is 

 tested to affect, metabolic action of any 

 enzyme (including any metabolic action 

 for which there is a specific Field T-2 

 symbol). Field T-2 is always coded with 

 the specific enzyme (see the special 

 Enzyme Code of Field T-2) rather than the 

 metabolic activity of the enzyme disturbed 

 by the test compound. See the Key. 



8 Tissues, cells, fluids (specific con- 



ditions or processes of tissues, cells, 

 fluids). Symbol 8 is not intended 

 particularly for use for coding even 

 unspecified conditions or processes. 

 It is intended here merely as a heading 

 for this series dealing with the struc- 

 tures indicated. 



81 Muscle activity 



811 Excitability 



8111 Refractory period. Do not use Symbol 

 8111 for the normal latent period 

 following muscle stimulation. 



812 Conduction (transmission) 



813 Contraction. Use Symbol 813 only for 



normal muscle contraction. Use other 

 symbols for abnormal contraction (e. g. , 

 contracture. Symbol 818; muscle spasm, 

 Symbol 8136, and muscle rigor. Symbol 

 819). 



8131 Force of normal contraction 



8132 Rate of normal contraction 



8133 Amplitude of normal contraction 



8134 Peristalsis 



8135 Spontaneous contraction other than 



peristalsis 



8136 Muscle spasm (including muscle 



twitching) 



814 Normal relaxation of muscle 



815 Action of specific anatomical muscles or 



muscle groups, unspecified. (Use 

 symbols of the 815- series to code a 

 result of muscle contraction or of mus- 

 cle relaxation, which may be caused 

 or affected by the test compound. For 

 example, flexions, extensions, con- 

 strictions, dilations, etc. of the body 

 of the animal or its parts. 



8151 Vasoconstriction (of the vessel specified 



in Field H-1 or Field H-2). Contraction 

 of the muscular coats of blood vessels. 

 This is not tantamount to increase in 

 blood pressure (Symbol 8211). 



8152 Vasodilation (of the vessel specified in 



Field H-1 or Field H-2). Relaxation of 



the muscular coats of blood vessels. 

 This is not tantamount to decrease in 

 blood pressure (Symbol 8212). 

 8153 Extension of the invertebrate (e. g. , 



moUuscan) body from its encasement, 

 shell, or tube. (Consult the Key. ) 



817 Tonus 



818 Contracture (prolonged contraction which 



is reversible; irreversible [permanent] 

 contraction is not contracture but rigor. 

 Symbol 819) 



8 1 9 Rigor 



81A Muscle fatigue 



81B Tetany 



81C Fibrillation of skeletal muscle. (For 



cardiac muscle fibrillations, see 



Symbol Series C . ) 



9A3 Tremor 



82 Body fluid pressure, unspecified as to 



which fluid. 

 821 Blood pressure, unspecified as to whether 



increased, decreased, venous, arterial, 



etc. Symbol 1 or 2 of Field T-1 may 



not be used with Symbol 821. Consult 



the Key. 



8211 Increased blood pressure (above the 



pressure characteristic of the individual 

 treated) due only to vasopressor action 

 which causes the increase in pressure 

 through vasomotor stimulation and vas- 

 cular constriction. (Vasoconstriction, 

 however, is not tantamount to an in- 

 crease in blood pressure. Use Symbol 



8151 for the specific state of vaso- 

 constriction. ) Use Symbol 8211 for any 

 vasopressor effect resulting in increased 

 blood pressure and caused by the test 

 compound (Symbol 7 of Field T- 1 ) or 



(as a symptom of a pathology) affected 

 by the test compound (Symbol 1 or 2 of 

 Field T-1). Do not use Symbol 821 1 

 for increased blood pressure due to any 

 cause other than vasopressor effect 

 (e. g. , do not use 821 1 for increased 

 pressure due to increase in blood 

 volume). Identify the vessel, artery 

 or vein, in Field H-1. 



8212 Decreased blood pressure (below the 



pressure characteristic of the indi- 

 vidual treated) due only to vasode- 

 pressor action which causes the de- 

 crease in pressure through vasomotor 

 depression and vascular dilation. 

 (Vasodilation is not tantamount to de- 

 crease in blood pressure. Use Symbol 



8152 for the specific state of vaso- 

 dilation. ) Use Symbol 8212 for any 

 vasodepressor effect resulting in de- 

 creased blood pressure and caused by 

 the test compound (Symbol 7 of Field 



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