FIELD X 

 Columns 69 and 70 



FIELD Y 

 Column 71 



Field X 



Field Y 



54 



Note: In the case of Criteria 54 and 57, below, the 

 reciprocal of the symbol used in Column 66 of Field U 

 is used on the abscissa scale of the Grid. (In essence, 

 this means merely that that abscissa scale of the Grid 

 is reversed. ) This is because a long duration of re- 

 sponse or long survival time increase or decrease rep- 

 resents a high level of chemical activity; for this same 

 reason, when basing evaluation on the time alone 

 (Criteria 13 and 12), the symbol coded in Field U is 

 used in Field Y rather than the reciprocal of that Field 

 U symbol. 



Duration of response (the time period 

 coded in Field U) vs. the cumulative per- 

 centage of individuals in which the re- 

 sponse endures the period coded in Field U. 



With Criterion 54, the evaluation to be 

 coded in Field Y is based on the point 

 at which the response has ended for any 

 given percentage of individuals. (Study 

 the example given in the Key, Specific 

 Directions and Explanations for Fields W, 

 X, and Y, Division 20. ) Evaluation sym- 

 bols: 1, 3, 5, 7, or 9, according to the 

 Grid area involved. 



57 Survival time increase or survival time 



decrease (the time period coded in Field U, 

 representing the time differential between 

 the survival times of treated and untreated 

 organisms) vs. the cumulative percentage 

 of individuals whose survival time was 

 affected to the degree indicated in Field U. 



With Criterion 57, evaluation is based on 

 the cumulative percentage of individuals 

 whose survival time has been increased 

 (or decreased) a given period. (Study 

 the example given in the Key, Specific 

 Directions and Explanations for Fields W, 

 X, and Y, Division 20. ) Evaluation sym- 

 bols: 1, 3, 5, 7, or 9, according to the 

 Grid area involved. 



Note: In the case of Criteria 58 and 59, below, the 

 symbol used in Column 66 of Field U is used on the 

 abscissa of the Grid. This is because a short time 

 to the specific action represents a high level of 

 chemical activity; for this same reason, when basing 

 evaluation on the time alone (Criteria 10 and 11), the 

 reciprocal of the symbol coded in Field U is used in 

 Field Y as an evaluation. 



58 Time to specific action other than death 

 (the time period from beginning of admin- 

 istration to the first appearance of the 

 response, coded in Field U), vs. the 

 cumulative percentage of individuals 

 responding within the time period coded 

 in Field U. 



With Criterion 58, evaluation is based on 

 the cumulative percentage of individuals 

 responding (other than by dying) after a 

 given period of time. (Study the example 

 given in the Key, Specific Directions and 

 Explanations for Fields W, X, and Y, 

 Division 20. ) Evaluation symbols: 1, 3, 

 5, 7, or 9, according to the Grid area 

 involved. 



189 



