CONTENTS 



Page 



FOREWORD 1 



FIELDS OF THE CODE; DESCRIPTIONS AND DIRECTIONS FOR THE USE OF 



SYMBOLS OF EACH FIELD IN CODING CHEMICAL- BIOLOGICAL INFORMATION. 



Field A: Physical State of the Test Compound; Dispersion or Non- 

 dispersion of the Test Compound; Indication that In- 

 formation on Correlation of Chemical Structure and 

 Biological Response Occurs in the Information Source 3 



Field B: Conditioning Agent; Miscellaneous Information about the 

 Test Compound Administration; Indication that in the 

 Data Source there is Information on the Effect of pH 

 on the Chemical Action 7 



Field C: Solvent or Vehicle for the Test Compound 10 



Field D: Secondary Compound 12 



Field E: Organism or Pathological Condition Treated 



General Discussion 18 



Taxonomy Code; Coding of Taxonomic Categories to 



Derive Field E Code Symbols for Organisms 25 



Tumor Code; Classification of Tumors and Derivation of 



Field E Code Symbols for Distinguishing /Identifying Tumors 31 



Pathology Code 



Introduction 38 



Derivation of Code Symbols for Pathologies, Information 



Coded in Field E about Specific Non-infectious Pathology 40 



Field F: Sex and Stage of Development of the Test Organism; 



Miscellaneous Information Concerning Tumors 45 



Fields G-l and G-2: Pretreatment or Experimental State of the Test Organism 



or of the Organ, Tissue, or Cell of the Test Organism 48 



Fields H-l and H-2: Gross Anatomy; Primary Anatomical Structures and 



Secondary Anatomical Structures 58 



Field I: Tissues, Cells, and Fluids 66 



Field J: Host Organism; Test Environment 68 



Field K: Sex and Stage of Development of the Host Organism 7 5 



Field L: Pretreatment or Experimental State of the Host Organism or of 

 the Organ, Tissue, or Cell (of the Host Organism) which is 

 the Site of the Parasite, Non-infectious Pathology, or Tumor 76 



Fields M and N: Dosage; Concentration of the Test Compound 



and Quantity of the Test Compound 82 



Field O: Dosage Frequency; Sequence of Administration of 



the Secondary Compound and the Test Compound 95 



