FIELD A 

 Column 9 



Field S-3, on the other hand, has as its objective the description of the route of the test 

 compound to or into the animal or plant, regardless of the condition of the compound. It is true that 

 certain routes would not be practical for all states in which the compound might be; nevertheless, the 

 use of Field S excludes any actual description of the condition of the compound- -except by implication 

 in specifying the route (e. g. , specifying in Field S "fumigation" or "inhalation" which implies appli- 

 cation of a compound as a mist or aerosol, but which makes no pretense at actually expressing by 

 code that condition of the compound). This is discussed also in Division 4 of the Specific Ejections 

 and Explanations for Field S-3. 



The third distinct use of Field A is discussed in Division 8 below. It is a means of retrieving 

 from the file of coded data those Biology Code Sheets containing literature (or other) references in 

 which the author has made observations on correlation of chemical structures and biological response 

 to those chemicals. The observations themselves are not coded nor are the details included in the 

 Code Sheet's written abstract of Field A; there is merely the coded indication in Field A that the infor- 

 mation can be found in the reference. In the written abstract portion of Field A, only a brief synopsis 

 is made of the specific correlations the author discusses in the article. 



Specific Directions and Explanations 



1. Coding in Field A when the test compound is applied to the test organism 



When the test compound is applied directly to the test organism in Field E (and when there is 

 no host coded in Field J), use the code symbol best describing the state of the test compound at the 

 time of application to the test organism. 



2. Coding in Field A when the test compound is applied to the host organism 



When the test compound is applied directly to the host ORGANISM (Field J) in or on which is 

 located the test organism (Field E), use the code symbol best describing the state of the test compound 

 at the time of application to the host. (See Division 5 for an exception, related to NON- LIVING hosts. ) 



3. Coding in Field A when the test compound is applied DIRECTLY to the test organism , 

 even when it is on or in a host 



When the test compound is applied directly to the test organism (Field E) on or in a host 

 (Field J) (e. g. , applied by dropping it on a tick attached to a dog or injecting it into a tapeworm cyst 

 in a rabbit), use the code symbol best describing the state of the test compound at the time of appli- 

 cation to the test organism. 



4. Coding in Field A when the test compound is applied to a host prior to inoculation 

 with the test organism 



When the test compound is applied to a host (or environment), coded in Field J, prior to the 

 introduction of the test organism , use the term which describes the state at the time of application to 

 the host, regardless of the state at the time the test organism is introduced. (See the following 

 division for an exception. ) 



5. Coding in Field A when the test compound is applied to a non-living host 



The provisions for application to hosts (Divisions 2 and 4 above) have as an exception the 

 situation in which the test organism is added to water , saline , or nutrient media , for example (i. e. , 

 inanimate, liquid or semi-liquid hosts or host environments coded in Field J), in which the pure test 

 compound (liquid, gas, or solid) has been dispersed in amounts to bring it to the test concentration 

 as coded in Fields M and N (by dissolution, emulsification, suspension, or mechanical mixing). In 

 this case, the host coded in Field J is the solvent or vehicle which is under other circumstances always 

 coded in Field C; the CBCC has not coded Field C in such instances--not necessarily because it would 

 represent coding duplication with Field J, but because many of the specific materials such as culture 

 media have not been included as items of Field C. Field C could be coded, if this host in Field J 

 happens to be also one of the specific items of Field C. Since coding Field A with liquid, gas, or 



4 - 



