FIELD E 

 Columns 18, 19, 20, 21, 

 22, 23, 24, and 25 



(B) When the specified major pathology is understood to be generally affected, either by 

 all the symptoms being affected in the same way or by the author's specifically stating 

 that one or more symptoms' responses are used merely as the author's basis for 

 determining that the major pathology is generally affected, the major pathology is 

 coded in Fields E and H, but the symptoms are not coded in Field T-2; instead, the 

 general response of the major pathology is coded by one of the symbols of the 17-- 



or 16-- series in Field T-2 and there is recorded, in the written abstract portion of 

 Field T-2, the evidence for that general effect on the major pathology. 



(C) When two or more coexisting pathological conditions are treated by a test compound 

 and they seem possibly related but there is no specific indication by the author that 

 these are all symptoms of a single major pathology nor is the coder absolutely confident 

 that these all represent a single major pathology, each condition must be coded in a 

 separate line in Field E; i. e. , each must be treated as a major pathology rather than 

 the coder's attributing one to being a symptom of the other or, by conjecture, attributing 

 both to a more general major pathology. 



6. Pathological conditions caused by test organisms (infectious diseases ) 



The Pathology Code of Field E considers that each parasitic organism, by its own specificity, 

 bears a unique relationship to its host and therefore causes a unique symptomatology, however small 

 might be the distinctions in certain instances. On this assumption, any pathological condition caused 

 by a specific organism can be defined most accurately by reference to that specific organism. There- 

 fore, in the Pathology Code, there are a number of items referring to the pathological conditions caused 

 by specific parasitic organisms and the symbol for each of these is merely the symbol for that parasitic 

 organism in the Taxonomy Code of Field E. In other words, the symbol for each such infectious disease 

 is exclusively etiological in nature, merely expressing the causative agent. The disease is made 

 specific, when necessary, only by indicating in Field H in what organ or part the infectious disease is 

 located. 



V. TEST ORGANISM IN WHICH PATHOLOGY IS PRODUCED BY THE TEST COMPOUND 

 ( Field T; NOT the Pathology Code ) 



As pointed out in Division 1 of Part IV, above, when a pathological condition is produced by 

 the test compound, the pathology is not coded in Field E, but it is coded by appropriate symbols in 

 Fields T-l and T-2, as the response to the test compound. The test organism in which this effect 

 occurs is coded in Field E. 



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