FIELDS H-l and H-2 

 Columns 29, 30, 31. 

 32, 33, and 34 



administered (Field S-3)--and a third for a site of a pathology coded in Field E when an organ other 

 than that specific pathology site (yet affected by the pathology) is the organ responding to the test 

 compound. However, the advantages of this were far outbalanced by advantages of restricting coding 

 to a single IBM punched card, which did not permit more than the single Field H-2- -used for all 

 purposes. Unfortunately, as a result, any entry in Field H-2, considered as an isolated entry, is 

 subject to any of three interpretations and therefore the meaning of any entry in Field H-2 can only be 

 learned by consulting Column 30, Field G and Field L, and Field S-3 (in that sequence), explained as 

 follows. 



If an organ in Field H-2 is the site of a pathology coded in Field E, an asterisk will be in 

 Column 30. (An explanation of the use of the asterisk and its importance is in Division 6. ) If the 

 organ in Field H-2 is in a special experimental state. Field G (or Field L) will be coded with one of 

 the following symbols: or P (or, less frequently, with S or T). If it is a specific organ to which 

 the test compound was directly administered, Field S-3 will be coded with one of the following symbols: 

 3, 4, 5, 7, 8, B, C, D, E, F, G, 1,0, P, S, or Z. 



As might be expected, an occasional experimental design will present a conflict in Field H-2 

 which the CBCC resolves by observing the following coding procedure: 



A. If a pathology coded in Field E is specifically of an organ other than the organ in Field H-l, 

 an asterisk is coded in Column 30 and Field H-2 must be used only for coding the site of 

 the pathology. 



B. If Field H-2 is not used for the special (and infrequent) purpose of A, above, and any of 

 Symbols 0, P, S, or T are coded in Field G- 1 or G-2, Field H-2 is used only for coding 

 organs in the experimental states designated by these Field G symbols. 



C. If Field H-2 is not used for purposes A or B, above, it can be used with Field S-3 to code 

 organs (other than the organ in Field H-l) to which the test compound is administered. 



This means that, in interpreting an entry in Field H-2, if an asterisk is coded in Column 30 

 (i. e. , a 12 zone punch in Column 30), any entry in Field H-2 represents the site of the pathology, 

 regardless of what is coded in Field G-l, G-2, L, or S-3. If Field G or Field L is coded with any of 

 Symbols 0, P, S, or T (and there is no 12 zone punch in Column 30), an entry in Field H-2 is always 

 an organ related to that special state coded in Field G or Field L. If Field G or Field L is not coded 

 with any of Symbols 0, P, S, or T (and no 12 zone punch in Column 30), an entry in Field H-2 is 

 always an organ to which the test compound was administered. 



4. Relationship between the anatomy coding (Fields H-l, H-2, and I) and Fields E (test 

 organism, pathology, or tumor) and J (host organism) 



In the previous section, General Use, the four general uses of Fields H-l and H-2 are explained. 

 Regardless of which of these four types of information is coded, there is the further matter of under- 

 standing the correct coding correlation to one or the other of the test organism and the host, since 

 there is only one area for coding anatomical structures and there are two places where organisms are 

 coded. 



If Field J is not coded (i. e. , if there is no host ), any coding of anatomy (Fields H-l, H-2, and 

 I) necessarily concerns only structures of the test organism. If there ij> a host organism , the anatomy 

 fields always are used only to name structures of that host coded in Field J. However, Field J may be 

 coded with non-living "hosts" (culture media, environments, etc.); since the anatomy fields have no 

 use relative to Field J in such cases, they may be used to code structures of the test organism coded 

 in Field E. (In Field J, non-living hosts have code symbols whose beginning units are restricted to 

 letters S through Z--i. e. , symbols distinguished by beginning units which are indicated on the IBM 

 punched card by combining numerical punches with the zone punch. ) 



In summary: When Field J is not coded , all coding in Fields H-l, H-2, and I designates 

 structures of the test organism in Field E. When Field J is coded with a host organism (symbols 

 beginning with any letter other than S through Z--i. e. , without the zone punch in Column 37), all 

 coding in Fields H-l, H-2, and I designates structures of the host organism. When Field J is coded 



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