FIELD I 

 Columns 35 and 36 



TISSUES, CELLS, AND FLUIDS 



Organization 



The list of histological and cytological anatomical structures is organized by natural groups and 

 assigned two-unit symbols (two IBM columns). The first unit indicates the general type of tissue and 

 the second indicates the specific tissue. For example, all symbols beginning with the digit 2 (Column 

 35) are connective tissues, while adipose connective tissue is specifically designated by the second 

 unit, digit 6 (Column 36). 



General Use 



The terms listed in this field are to be used in conjunction with Field H- 1 (primary organs), to 

 permit specific description of finer anatomical structures responding to test compounds. Occasionally, 

 a tissue from Field I may be used in absence of an entry in Field H- 1, when the organ is not specified 

 in the article or when the tissue is not restricted to a single organ system. 



Field I is coded only to relate to Field H- 1 and never to an organ in Field H-2. 



When Field E is used to code a pathology or a tumor, Field I, as well as Field H-l, is used only 

 to describe the anatomical location of the tumor or pathology. 



Specific Directions and Explanations 



1. Use of terms of Field I which are identical to terms of Field H 



Several terms occur in both Field H and Field I, due to anatomical complexity. For example, 

 most organs are supplied with blood vessels and nerves, each of which can be considered themselves 

 as organs. These structures which can be anatomical parts of more gross organs are included in Field 

 I as well as Field H. Thus, when blood vessels of a specific organ are affected, it is possible to code 

 the particular vessels by combined use of Fields H- 1 and I. On the other hand, if blood vessels are 

 generally affected, regardless of their relationship to specific organs, they can be coded in Field H- 1 

 as the organ affected. The following examples demonstrate the foregoing. 



Example 1. The test compound caused inflammation of arterial walls as evidenced by 

 observations on the femoral artery. 



Field T-l Field T-Z Field H-l 



7 1132 325 



(produces) (inflammation) (of the arteries) 



Example 2. In studying factors which affect the kidney blood flow, the test compound was 

 found to produce inflammation of the nephric (kidney) blood vessels. 



Field T-l Field T-2 Field H-I Field I 



7 1132 71 CI 



(produces) (inflammation) (of the kidney) (blood vessels) 



2. Certain tissues included in Field H as organs: blood, lymph, and reproductive cells 



While blood is commonly considered as a specific tissue, the collective blood mass can at the 

 same time be justifiably regarded as an organ constructed of but a single tissue. Lymph might similarly 

 be regarded as an organ. If either were coded in Field I, as a tissue responding to the test compound, 

 there would seldom be anything of significance (i. e. , only "blood vessel" or "body as a whole") needed 



66 



