F IELD I 

 Columns 35 and 36 



in Field H, although to imply by such coding that a blood vessel or the body as a whole is affected 

 because the fluid it contains is affected would be inaccurate. Therefore, blood and lymph are coded 

 in Field H and are not included among the Field I items as tissues. There has been no occasion when 

 "blood" has been needed in Field I to specify a tissue of a particular organ coded in Field H-l. I. e. , 

 "arterial blood", "venous blood", "renal blood", "cerebra 1 blood", etc. , have not been distinctions 

 the CBCC has found a necessity to make. However, if this is necessary, these particular designations 

 can be added to Field H with new symbols of the 33 -series. 



Sexual reproductive cells are confined to the two structures, ovary and testis, although, in the 

 normal course of events, they are discharged from the ovary or are propelled from the testis to traverse 

 paths through other structures. Therefore, though they are by nature cells (or germinal tissues) rather 

 than organs, their being coded in Field I, with ovary or testis coded in Field H-l, most often would 

 represent a redundancy (i. e. , when sperm or ovum is coded, it may be assumed that they are in the 

 testis or ovary or parts thereof). For this reason, the CBCC codes sperm and ovum in Field H, for the 

 sake of expedience. If for some reason it becomes important to distinguish sperm of the seminiferous 

 tubules from sperm of the epididymis, for example, the Code may be modified by adding new specific 

 items to Field H (seminiferous tubule sperm, vasa efferential sperm, epididymal sperm, etc. ) or by 

 adding sperm (and ovum) to Field I. 



3. Symbol 64; the test compound's effect on a product of a gland 



When a normal component of a glandular product is increased or decreased in quantity by the 

 test compound, the effect is coded with one of the FC-- symbol series in Field T-Z, with Field T- 1 

 Symbols 1, 2, 3, 4, or 5. However, there is no way of indicating by this coding in Field T-2 whether the 

 component of the gland's secretion is produced in abnormal amounts due to merely altering the total 

 volume of the gland's secretion or due to altering the relative composition of the secretion. Symbol 64 

 has been provided in Field I to distinguish these two effects of the test compound (though doubtless 

 secretions are not ordinarily considered to be body fluids). The symbol indicates that the test compound 

 affects that total secretory product (of the gland coded in Field H-l) in the manner indicated in Field T, 

 by altering its basic c haracter (i. e. , by altering its composition relative to the component specifically 

 coded by the Field T-2 symbol) rather than altering merely its volume. Therefore, when only volume of 

 the total secretion has been altered, though the components of the secretion remain proportionately 

 normal per unit volume, Symbol 64 must NOT be used in Field I. 



4. Symbols available for additional items of Field I 



None of the IBM zone punches have been assigned a special meaning in Field I. Therefore, 

 there are no restrictions in use of any letters in either column for constructing symbols. 



5. File of coded biology data on IBM punched cards arranged according to symbols for tissues 

 and cells 



The CBCC maintains a special IBM punched card file for all cards on which Field I has been 

 coded, arranged according to Field I code symbols. Thus, all coded data in which a given tissue is 

 affected by test compounds, or in which was located a pathology that is affected by test compounds, 

 can be taken quickly and by manual selection from this file. 



6. Double coding is not permitted in Field I. 



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