FIELD L 

 Column 44 



15. Indications that an EXTIRPATED organ or tissue (site of pathology) is WHOLE (Symbol R) vs. the 

 indication that the organ or tissue has been macerated, sliced, etc. (Symbols U, V, W, and X ). 

 (Refer to Division 15 of Specific Directions and Explanations for Field G, applying that discus- 

 sion to Symbols R, U, V, W, and X of Field L. ) 



16. Symbols U, V, W, and X describe states of the host (or organ or tissue of the host) AT THE TIME 

 OF CHEMICAL TREATMENT 



When a compound is applied to a host organism (or organ or tissue site of pathology) which is 

 later homogenized or made into slices or extracts, etc. , for the purpose of reading the test results, 

 Code Symbols U, V, W, and X can not be coded in Field L. This field is used only to describe the 

 state or condition of the host or site of pathology at the time of treatment . 



17. Symbol Y: resistance acquired to the test organism 



This symbol represents a factor unique to Fields L and J in that the host can develop an immunity 

 to the biological factor coded in Field E against which the test compound is being administered. This 

 is a factor that frequently deserves or demands recognition in recording and evaluation of a therapeutic 

 action of a test compound. 



18. Symbol Z 



This symbol is used in a unique way and does not correspond to the other symbols of Field L in 

 that it does not represent just a pretreatment or state of the host during the test, but it represents, like 

 the test compound, an active factor of therapy for the parasite, non-infectious pathology, or tumor. 

 When this symbol is used, it indicates a therapeutic treatment given to the host (which may be in any 

 experimental state indicated by any of Symbols 1 through Y), in conjunction with the test compound 

 treatment (or test compound and secondary compound treatment). When any such test compounded of 

 chemical and non-chemical treatment is coded, Symbol Z has precedence over any symbol for pretreat- 

 ments and experimental states in Field L and the latter can only be recorded in the written abstract. 



The CBCC Code makes no provision for identification of such non-chemical therapeutic treatment 

 so that there is no way of distinguishing two or more tests (i. e. , two or more code lines) according to 

 variation in non-chemical therapy. A coding project concerned particularly with clinical data would 

 doubtless find advantageous devising specific symbols, rather than a single non-specific symbol 

 (Symbol Z), for various non- chemical therapeutic treatments. 



19. Symbols available for additional items of Field L 



All numerical and letter symbols available for Field L have been used. However, since the IBM 

 zone punches have not been given special meanings in Field L, each of them can be used alone as a 

 symbol. 



20. File of coded biology data on IBM punched cards arranged according to symbols for experimental 

 states of host 



The CBCC has not established a s'pecial file of coded data in which Field L has been used (and 

 arranged by Field L symbol sequence), because of the remote probabilities of a frequent need to search 

 for all information on tests in which was a specific incidental condition of the host. The coding of 

 Field L is more frequently used in "secondary" sorting of coded information and should be regarded as 

 a means of recording biological aspects of chemical therapeutic tests that are frequently of prime sig- 

 nificance in explaining the outcome, coded in Fields T, W, X, and Y. 



21 . Double coding is not possible in Field L 



Having made use of all of numbers 1 through 9 and all 26 letters for code symbols in Field L, 

 the IBM machine punching and retrieval procedures do not permit more than a single symbol in Field L 

 in any one line. Therefore, when coding two or more tests whose details and outcomes are so nearly 

 alike that the code lines for all tests would be identical except for differences in pretreatment or state 

 of the host (Field L), the tests can not all be recorded by one code line with several entries (repre- 

 senting the several pretreatments or states) in Field L. (A special circumstance allows condensing 



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