FIELD R 

 Column 53 



When an author indicates only that implantation, inoculation, etc. , was on the "day of the 

 last dose" (in cases of multiple doses of the test compound), without specifying whether the time 

 between the last dose and implantation was less than or more than an hour after the last dose, use 

 Symbol C. In the same way, when it is known only that implantation, inoculation, etc. , was on the 

 "day of the first dose of the test compound" or was "immediately after", use Symbol 2. 



In the case of a single or continuous administration of the test compound, if the author only 

 states that the test compound administration was "on the same day" as the implantation, inoculation, 

 etc. , without specifying which operation was performed first, use Symbol 1. 



When the author states that treatment is administered "on the day following" (or "prior to") 

 implantation, etc. , there is posed the question as to whether the time interval was greater than, 

 equal to, or less than 24 hours. Symbol 3 (or Symbol D in the case of "prior to") is to be used in 

 these cases merely for consistency, since Symbols 2 and C are used for coding the expression "on 

 the same day". 



7. In vitro experiments 



Field R may be used for indicating time between time of treatment and time of inoculation of 

 in vitro tests as well as in vivo tests. 



8. Symbols available for additional items of Field R 



Inasmuch as the IBM zone punches have not been assigned for special purposes in Field R, 

 any of the presently unused letters can be used as symbols (i. e. , N through Z), although it seems 

 probable that the time periods already designated in the field are adequate. 



9. File of coded biology data on IBM punched cards arranged according to symbols for time 

 periods of Field R 



The CBCC has not established a file of coded biology data arranged by Field R symbols because 

 of the improbability of beginning an information search by looking for inoculation- treatment relation- 

 ships of tests. 



10. Double coding in Field R 



When the evaluations of two or more tests are so similar that they can be coded by the identical 

 symbol in Field Y and the only difference between the two or more tests is the period between implanta- 

 tion, inoculation, etc. , and administration of the test compound, all the time periods may be coded 

 in Field R in one line and all punched on the same IBM card. This is double coding. Double coding 

 in Field R has restrictions, however; IT IS POSSIBLE ONLY IF THE SYMBOLS DOUBLE CODED ARE 

 NUMERICAL, SYMBOLS 1 THROUGH 9. The IBM procedure will not permit double coding of two letter 

 symbols or a letter and numerical combination. 



107 



