FIELD T-2 

 Columns 58, 59, 60, and 61 



even though the factors themselves, such as abnormal blood volume, vasodilation, vasoconstriction, 

 sclerosis, etc. , do have Field T-2 symbols: blood pressure increase due to increased blood volume, 

 decreased pressure due to decreased blood volume, pressure changes known to be due to direct action 

 on vessel musculature (vasodilation, vasoconstriction) rather than due to indirect action on vessel 

 musculature (vasomotor action, Symbols 8211 and 8212), pressure increase due to loss of elasticity of 

 vascular walls, etc. 



25. Symbols F6--, F8--, F9--, FA--, FB--, FC--, FG--, FH--, and FI-- 



General explanation has been made in the Code for the use of these symbols, but it has not 

 been convenient to include with their definitions in the Code all the instructions and explanations 

 important to understanding their use. For each symbol, these additional comments are included here: 



Nutrient uptake 



F6--: Use Symbol F6-- only to code the physiological process (uptake of nutrients) at the 



cellular level of the organism. For the process of feeding or ingestion, use Symbol F3. 

 Symbol F6-- is used also for the process of a plant's taking materials from the soil, 

 water, or other medium in which it is growing, as well as for the uptake of these 

 materials (and the plant's distributed photosynthetic products) by the plant's tissues. 

 Since test compounds are not considered to be nutrients, Symbol F6-- will not be 

 combined with Symbol B to form the composite Symbol F6B. 



Chemo synthesis 



F8--: Since the CBCC does not code information about normal metabolism, the organism's 

 ability to synthesize the test compound would not be coded, unless Field E is coded 

 with a pathology one of the symptoms of which is the abnormal synthesis of the test 

 compound. Only under this situation can Symbol F8-- be combined with Symbol --B 

 to form the composite Symbol F8B. Symbol F8-- is to be used for coding production 

 of the compound; although it is defined in terms of synthesis, the symbol can be used 

 whether the compound is formed by the organism through actual synthesis or as the 

 result of a breakdown of a larger molecule. 



Distribution 



F9--: Use Symbol F9-- for translocation and migration of nutrilites and metaooiites from the 

 sites of origin or storage. Code in Field H-l the site from which distribution is made, 

 unless the distributed material is fed, injected, or otherwise administered, when the 

 site of administration need not be coded in Field H-l. Distribution of the test compound 

 is not to be coded (except in the case of its being concentrated or stored, which is coded 

 by use of Symbol FA--) and therefore Symbol F9-- can not be combined with Symbol --B 

 to make the composite Symbol F9B. 



Storage, deposit 



FA--: Code in Fields H-l and/or I the site of storage or deposit. Do not use Symbol FA-- 

 with Symbol 2 of Field T- 1 to indicate withdrawal of material from a given site, but 

 use Symbol 2 only to code a decrease (from normal) of the rate of deposit or a decrease 

 (from normal) of the total quantity; to code a withdrawal, use only Symbol FI--. Symbol 

 FA-- can be combined with Symbol --B to make the composite symbol FAB with which 

 only Symbol 7 can be used in Field T-l. 



Absorption 



FB--: Code in Fields H-l and/or I the site of absorption. Use Symbol FB-- for the selective 

 resorption Into the blood of materials from the renal tubule. (For the general process 

 of filtering the blood at the renal corpuscle, use Symbol 87 Bl. For the general renal 

 process resulting in excretion of a specific material in the urine, use Symbol FC-- 

 or FF1-. ) 



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