FIELD T-2 

 Columns 58, 59, 60, and 61 



circumstances, the foreign material excreted, secreted, or vomited, if its specific identity is known, 

 is written, not coded, in Field T-2. 



28. Use of symbols of series FC-- compared to use of symbols of series FF--; coding of general 

 functions of excretory and exocrine secretory structures 



The processes of excretion and secretion do not lend themselves easily to being classified 

 separately; many "excretory" organs are quite legitimately regarded as secretory and many "secretory" 

 organs certainly serve as paths for excretion. Excretion and exocrine secretion are treated together in 

 this Code, for purposes of coding the processes of an organism's discard or loss of chemical materials. 

 (Endocrine secretion is not included in the category of metabolic activities dealing with discard and 

 loss. ) Instead of attempting to distinguish between excretion and exocrine secretion, the Code distin- 

 guishes between (1) normal discard and loss which a test compound (or secondary compound) can effect 

 (FC--) and (2) the test compound's discard or loss (FF-B); the second of these two categories (which 

 represents discard or loss of a foreign material, the test compound) is expanded in definition to provide 

 symbols for coding the discard or loss of any foreign material (FF-1 through FF-L). 



Effects of test compounds on the processes of discard or loss from the organism are most fre- 

 quently in terms of an effect on the loss of a specific material or a specific type of material , whether 

 it is normal or foreign. Thus, the test compound may be described as decreasing, increasing, or stop- 

 ping discard or loss of a carbohydrate, a protein, a hormone, etc. It is for this effect on metabolic 

 loss of specific materials that symbols of series FC-- are ordinarily used and for which symbols of the 

 FF-- series (except FF-B) are invariably used. However, a test compound's effect can be in terms of 

 merely an effect on the general activity of an excretory or exocrine secretory organ or tissue, without 

 indicating that any one of the many specific materials the organ or tissue may normally secrete or 

 excrete is specifically affected. To code this effect of the test compound, symbols of the FF-- series 

 should never be used, but only FC (with nothing coded in Columns 60 and 61), coding the specific 

 excretory organ or exocrine gland or glandular tissue in Fields H-l and/or I. This latter coding in 

 Field T-2 is preferred over using Symbol 15, since it is more specific. 



29. Symbols available for expansion of Field T-2 



Examination of the Code will reveal that an enormous number of symbols remain available for 

 new biological conditions, qualities, or processes which can be caused or affected by test compounds 

 or secondary compounds. This is true not only for new series (Symbols E through Z in Column 58), but 

 within series (Columns 59 through 61), since in none of the series have the items been so numerous 

 that all symbols of any one column have been exhausted through Symbol Z. Only one restriction exists 

 which was pointed out earlier. With symbols of the FE-- series, Symbols A through I can not be used 

 in Column 61, since Symbol * (the IBM 12 zone punch) is used in that column for a special purpose 

 with that series of symbols. 



30. File of coded biology data arranged by biological state, quality, or process 



The CBCC maintains a file of its coded biology data on IBM punched cards arranged according 

 to entries in Field T-2 so that information about any specific biological state, quality, or process that 

 can be caused or affected by test compounds (or information about any specific alteration of test 

 compounds) can be retrieved manually. This is because so much retrieval of coded information is begun 

 most efficiently by sorting for these particular entries. 



31. Double coding in Field T-2 



Field T-2 is never to have more than a single entry in any one code line, except that Symbol * 

 may be coded with symbols of the FE-- series in Column 61 as explained in Division 26. When Sym- 

 bol * is coded in Column 61 (representing essentially the coding of two categories of information, 

 rather than double coding), both it (the 12 zone punch) and the numerical or letter symbol accompanying 

 it in the column are punched on the same IBM card in that column; a second card is not punched with 

 the 12 zone punch omitted. In the IBM Punched Card File arranged according to entries in Field T-2, 

 the card is filed in the sequence indicated by the code symbol for the secondary or a third chemical's 

 alteration. 



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