130 OOPTIS. No. 2r. 



a pure bitter is required ; being a good substitute for 

 Quassia, Columbo, Gentian, &c. A tincture made 

 with an ounce of the roots in a pound of diluted alco- 

 hol, is recommended in doses of a tea spoonful thrice 

 a day, or ten to twenty grains of the powder: both 

 agree with the stomach. 



It has been used for ulceration of the mouth, in gar- 

 gle, &e. but Bigelow pretends that it is inert in that 

 case, being devoid of astringency ; and to other arti- 

 cles added to it, are to be ascribed the benefit it may 

 have afforded. 



Substitutes — Quassia — Columbo — Menyanthes 

 trifoUata — Frasera verticillata — Jlletrisfarinosa" 

 Sabbatia angularisj and other pure bitters. 



