X-ray Analyses of Proteins and Nucleic Acids 297 



including those of chemistry, physics, crystallography, biochemistry, 

 genetics, and virology have all been synthesized to elucidate the structure 

 of proteins and nucleic acids. The task is far from complete and one 

 may anticipate continued development of these techniques. 



REFERENCES 



Biochemistry 



A number of good general biochemistry texts describe the properties of 

 proteins and nucleic acids. The author suggests : 



1. Kleiner, I. S., and J. M. Orten, Human Biochemistry, 5th ed. (St. Louis, 

 Missouri: C. V. Mosby Company, 1958). 



The standard text on nucleic acid is : 



2. Chargaff, Edwin, and J. N. Davidson, The Nucleic Acids: Chemistry and 

 Biology (New York: Academic Press, Inc., 1955) 2 vols. 



X-ray Diffraction 

 As a general introductory text, the author prefers : 



3. Semat, Henry, Introduction to Atomic and Nuclear Physics, 3rd ed. (New 

 York: Holt, Rinehart & Winston, Inc., 1954). 



A more advanced discussion can be found in : 



4. McLachlan, Dan, X-ray Crystal Structure (New York : McGraw-Hill Book 

 Company, Inc., 1957). 



Journal Articles 



The reader is strongly encouraged to read as many of the following journal 

 articles as possible: 



5. Watson, J. D., and F. H. C. Crick, "A Structure for Deoxyribose Nucleic 

 Acid," Nature 171: 737-738 (Apr. 25, 1953). 



a. "Genetical Implications of the Structure of Deoxyribonucleic Acid," 

 171: 964-967 (May 30, 1953). 



6. Pauling, Linus, and R. B. Corey, "Configuration of Polypeptide Chains," 

 Nature 168: 550-551 (Sept. 29, 1951). 



7. Cochran, W., F. H. C. Crick, and V. Vand, "The Structure of Synthetic 

 Polypeptides. I. The Transforms of Atoms on a Helix," Acta Cryst. 5: 

 581-586 (1952). 



8. Gamow, George, "Information Transfer in the Living Cell," Scientific Am. 

 193: 70-84 (Oct. 1955). 



9. Franklin, Rosalind E., "Structure of Tobacco Mosaic Virus," Nature 175: 

 379-381 (Feb. 26, 1955). 



