GLUCOSE 



CH3-CO-COOH 

 PYRUVATE 





 II 

 CHj-C-S-Co A 



ACETYL CoA 

 i 



NHg-CH-COOH 

 CH2-COOH 

 ASPARTIC ACID 



CO-COOH 



I 



CH2-COOH 



OXALACETIC ACID 



HO-CH-COOH 

 I 

 CH2-COOH — ^ 



MALIC ACID 



CH-COOH 

 II 

 CH-COOH 



FUMARIC ACID 



w 



SPORE ^ CH2-COOH 



CHO 



I 



COOH 



6LY0XYLIC ACID 



MATERIAL 



I 

 CH2-COOH 



SUCCINIC ACID 



w 



CHp-C-SCoA 

 I ^ 

 CH2-COOH 



SUCCINYL CoA 



COOH 

 / 

 CH3-CH 



CH3-CH2 



PROPIONYL Co A 



i 



CH3-CH2-COOH 



PROPIONIC ACID 



C~SCoA 

 METHYL MALONYL CoA 



'0 

 II 

 C-SCo A 



COOH 

 I 

 CO 



I 



CHp 



I 

 CHo 



I ^ 

 COOH 



CH2-COOH 



I 

 HO-C-COOH 



I 

 H2-C-COOH 



CITRIC ACID 



;- KETOGLUTARIC ACID 



COOH 



I 

 CH-NHp 



I 

 CHp 



I 

 CH2 



^00 H _ 



GLUTAMIC ACID 



H-C-COOH 

 II 



C-COOH 

 I 

 CH2-COOH 



CIS-ACONITIC ACID 



HO-CH-COOH 

 I 



CH-COOH 

 I 

 CH2-COOH 



ISOCITRIC ACID 



CO-COOH 



I 

 CHp-COOH 



I 

 CH2-COOH 



OXALOSUCCINIC ACID 



Figure 11. Tricarboxylic-acid cycle with the glyoxyhc-acid shunt. 



