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indicators, mainly due to the condition of air in the atmosphere. The environmental 

 effects are related to climatic factors as well as to the quality of drinking water. The 

 effect of these factors on health indicators are manifested in the form of mass or 

 sporadic morbidity with certain therapeutic and infectious diseases. 



Study of the dynamics of general morbidity among adults and teenagers in 

 Magadan indicates an unfavorable trend. Thus, the total morbidity increased by 2.2 

 times from 1979 to 1989, while the number of new cases increased by more than 5 times. 

 A particularly unfavorable morbidity pattern emerged among children. From 1979 to 

 1989, the total morbidity increased by almost 10 times. 



Adults and teenagers show a high rate of increase in the incidence of diabetes 

 mellitus (by 2 times), and cardiovascular diseases (by more than 3 times), etc. 



The Far East is characterized by a complex ecological situation, including a 

 radiation element, and complex medico-demographic processes. A monsoon climate 

 combined with the conditions of an anthropogenic load causes substantial stress to the 

 adaptation mechanisms of both indigenous and immigrant populations, resulting in high 

 morbidity. The incidence of respiratory diseases is 429.0 per 1,000 people; diseases of 

 the nervous system, 101.0; diseases of the digestive organs, 89.0; infectious pathology, 

 59.7; including 2.8 tuberculosis cases (for the Russian Federation the corresponding 

 figures are 401.0; 104.0; 8&0; 52.0; and 2.0. ■ 



There is a high level of traumas and poisonings; oncological morbidity is on the 

 rise. Total mortality in the Far East is 7.8 per 1,000 (in the Russian Federation it is 

 10.7). 



Somatic diseases were found for the first time in 20.5% of examined patients, 

 including otorhinolaryngological diseases, 33.6%; eye diseases, 66.3%; neurological 

 disorders, 5U%; 18% of workers were found unfit for work under hazardous working 

 conditions and a change in occupation was recommended; occupational "risk groups" who 

 needed observation and rehabilitation were identified. 



Preliminary investigations made it possible to reveal disruptions in the cellular 

 link of immunological reactivity not only in the sick, but also in individuals who consider 

 themselves to be practically healthy, although affected by the ecological fectors under 

 study. This group retains the phagocytic reserve, but the phagocytic activity of 

 neutrophils is reduced, and the proportion of individuals with critical deviations in the T- 

 lymphocyte count increased, which made it possible to include them in the risk group for 

 the development of immunodeficiency. 



Individuals who arrived from other regions of this country (Siberia, the Urals, the 

 Euro{)ean region) have a higher level of humoral indices such as natural antibodies, 

 blood serxmi lysozyme, or serum immunoglobulins of classes A,M,C The results indicate 



