SPOROTRICHOSIS 193 



LITERATURE 



1. CoNANT, N. F., A cultural study of the life-cycle of Histoplasma capsulatum 



Darling 1906, J. Bad., 41, 563 (1941). 



2. Darling, S. T., A protozoan general infection producing pseudotubercles in 



the lungs and focal necrosis in the liver, spleen and lymph nodes, J. Am. 

 Med. Assoc, 46, 1283 (1906). 



3. , The morphology of the parasite {Histoplasma capsulatum) and the 



lesions of histoplasmosis, a fatal disease of tropical America, Jour. Exptl. 

 Med., 11, 515 (1909). 



4. DeMonbreun, W. a., The cultivation and cultural characteristics of Dar- 



ling's Histoplasma capstdaium. Am. J. Trop. Med., 14, 93 (1934). 



5. DoDD, K., and E. H. Tompkins, A case of histoplasmosis of Darling in an 



infant. Am. J. Trop. Med., 14, 127 (1934). 



6. Emmons, C. W., B. J. Olson, and W. W. Eldridge, Studies of the role of 



fungi in pulmonary disease, I. Cross reactions of histoplasmin. Public 

 Health Repts., 60, 1383 (1945). 



7. Hansmann, G. H., and J. R. Schenken, A unique infection in man caused 



by a new yeast-like organism, a pathogenic member of the genus Sepe- 

 donium, Am. J. Path., 10, 731 (1934). 



8. Henderson, R. G., H. Pinkerton, and L. T. Moore, Histoplasma capsulatum 



as a cause of chronic ulcerative enteritis, /. Am. Med. Assoc, 118, 885 

 (1942). 



9. Humphrey, A. A., Reticuloendothelial cytomycosis (histoplasmosis of Dar- 



ling), Arch. Internal Med., 65, 902 (1940). 



10. Meleney, H. E., Histoplasmosis (reticulo-endothelial cytomycosis) : a re- 



view. Am. J. Trop. Med., 20, 603 (1940). 



11. Moore, M., and L. H. Jorstadt, Histoplasmosis and its importance to oto- 



rhinolaryngologists. A review with report of a new case, Ann. Otol. 

 Rhinol. Laryn., 52, 779 (1943). 



12. Parsons, R. J., and C. J. D. Zarafonetis, Histoplasmosis in man, Arch. 



Internal Med., 75, 1 (1945). 



13. Van Pernis, P. A., M. E. Benson, and P. H. Holinger, Specific cutaneous 



reactions with histoplasmosis, /. Am. Med. Assoc, 117, 436 (1941). 



SPOROTRICHOSIS 



The genus Sporotrichum is characterized by the prockiction of pear- 

 shaped conidia on minute apiculate processes. The first conidia pro- 

 duced by a culture are usually borne at the tips of short simple 

 conidiophores. As the culture ages the conidia are borne laterally 

 on the conidiophores and on the undifferentiated hyphae. Thus, in 

 an old culture there are very numerous dark or smoky-colored conidia 

 borne at the tips of conidiophores and forming sleeve-like masses 

 around conidiophores and hyphae. 



Clinical. There are two portals of entry, through wounds and 

 through the alimentary tract. The great majority of human cases 



