134 STATE BOARD OF AGRICULTURE. 



through the puncture wouud. Do not try to inject the material just 

 under the skin as is customary in hypodermic injections. 

 Use a slip needle of rather small calibre. 



Note. — Needles are frequently broken off in tbe flesh and should be removed when pos- 

 sible, i. e., when they can be secured before becoming buried under the skin. A local 

 abscess usually re.sults upon failure to remove a broken needle. 



Make it a practice to inject serum on the left side and virus on the 

 right side so that, if local trouble results, it can be attributed to its 

 proper source. 



In case of leakage due to stoppage of needle or other causes, be sure 

 that the proper amount of serum and virus is introduced before the 

 pig is set free. 



It is well to wipe off the point of inoculation of the virus with a 

 cloth dipped in disinfecting solution after injection. 



Permanent separation of sound from atfected animals and thorough 

 disinfection of premises are advisable, but not mandatory. 



The price of serum and virus at present is at the rate of two cents 

 per cc. for serum and one cent per cc. for virus. 



Do not fail to make out contracts in duitlicate, filling in all blanks 

 and adding any details of interest. Return one contract, report once 

 each week as to results, and address all communications to, 



BACTERIOLOGICAL LABORATORY, 



East Lansing, Michigan. 



We now think that we are in position to produce a circular which 

 will set forth the value of serum for checking hog cholera outbreaks, 

 but shall not recommend the use of virus unless employed by our own 

 hands. In other words, we can recommend the "Serum-Alone" method 

 as one quite free from danger and capable of checking the disease in 

 most herds, but the "Simultaneous Method" we do not recommend, be- 

 cause it is too dangerous to use indiscriminately at the present time. 

 We, hope, however, that the latter method can be perfected, because it 

 is the better method. 



The results for the year may be set forth in the following table. 

 On the wliole, they may be regarded as very satisfactory, but there are 

 some disastrous results which may or may not be accounted for. From 

 July till the middle of November our results were uniformly satis- 

 factory — as satisfactory as can be exjjected from serum under all con- 

 ditions. About the middle of November, a cold wave came on, and a 

 new lot of serum Avas employed. We received our first check. The 

 material was used upon five herds. During the winter, we learned that 

 ])Oor serum can be produced unless certain features of manufacture are 

 watched verv carefullv, and even wlien thev are carefullv watched. 

 Again, cold weather and the individual variation in swine affect the 

 manufacture of a serum as Avell as the treatment. To avoid disastrous 

 results, we now test out as best we can every lot of serum, and also do 

 not recommend its use in cold weather, unless necessity drives us to 

 some treatment. Herewith, I api)end the table prepared by Dr. Giltner. 



