742 A MANUAL Ot THE PENICILLIA 



Ctdture Media and Production Methods 



Abraham, E. P., Chain, E., Fletcher, C. M., Gardner, A. D., Heatlet, N. G., 

 Jennings, M. A., and Florey, H. W. 1941. Further observations on 

 penicillin. Lancet 241: 177-189, 2 figs., 2 diags., 4 graphs. 

 BowDEN, J. P. AND Peterson, W. H. 1946. The role of corn steep liquor in the 



production of penicillin. Arch. Biochem. 9: 387-399. 

 Burkholder, P. R. and Sinnott, E. W. 1945. Morphogenesis of fungus colonies 



in submerged shaken cultures. Amer. Jour. Bot. 32: 424-431, 2 figs. 

 Clifton, C. E. 1943. Large-scale production of penicillin. Science 98: 69-70. 

 Clutterbuck, p. W., Lovell, R., and Raistrick, H. 1932. Studies in the bio- 

 chemistry of micro-organisms. XXVI. The formation from glucose by 

 members of the Penicillixim chrysogenum series of a pigment, an alkali-solu- 

 ble protein and "penicillin"— the antibacterial substance of Fleming. Bio- 

 chem. Jour. 26: 1907-1918. 

 Cook, R. P. and Brown, M. B. 1946a. Penicillin production on juices from various 

 parts of the pea plant. Biochem. Jour. Abs. 40: 22-23. 



and Brown, M. B. 1946b. Penicillin production on fractions from the pea 



{Pisum sativum). Biochem. Jour. Abs. 40: 34. 

 and Brown, M. B. 1946c. Synthetic media for penicillin production. Bio- 

 chem. Jour. 40: 49-50. 



— , Tulloch, W. J., Brown, B., and Brodie, J. 1945. The production of 



penicillin using fractions obtained from aqueous extracts of pea (Pisum 

 sativum). Biochem. Jour. 39: 314-317, 1 fig. 

 Ettlinger, L. 1946. Zur kulturellen Gewinning von Penicillin. (On the cultural 

 production of penicillin). Schweiz. Bot. Gesell, Ber. 56: 681-695, 3 figs., 

 3 graphs. 

 Foster, J. W., McDaniel, L. E., Woodruff, H. B., and Stokes, J. L. 1945. Mi- 

 crobiological aspects of penicillin. V. Conidiospore formation in sub- 

 merged cultures of Penicillium notatum. Jour. Bact. 50: 365-368, 3 illus. 



, Woodruff, H. B., and McDaniel, L. E. 1943. Microbiological aspects of 



penicillin. III. Production of penicillin in surface cultures of Penicillium 

 notatum. Jour. Bact. 46: 421-433, 1 illus. 



, Woodruff, H. B., and McDaniel, L. E. 1946. Microbiological aspects of 



penicillin. IV. Production of penicillin in submerged cultures of Peni- 

 cillium notatum. Jour. Bact. 51: 465-478, 1 graph. 



, Woodruff, H. B., Perlman, D., McDaniel, L. E., Wilker, B. L., and 



Hendlin, D. 1946. Microbiological aspects of penicillin. IX. Cotton- 

 seed meal as a substitute for corn steep liquor in penicillin production. 

 Jour. Bact. 51: 695-698. 

 Gilbert, W. J. and Hickey, R. J. 1946. Production of conidia in submerged cul- 

 tures of Penicillium notatum. Jour. Bact. 51: 731-733. 

 Higuchi, K., Jarvis, F. G., Peterson, W. H., and Johnson, M. J. 1946. Effect 

 of phenylacetic acid derivatives on the types of penicillin produced by 

 Penicillium chrysogenum Q176. Amer. Chem. Soc. Jour. 68: 1669-1670. 

 Johnson, M. J. 1946. Metabolism of penicillin-producing molds. N. Y. Acad. 



Sci. Ann. 48: 57-66, 4 figs. 

 Knight, S. G. and Frazier, W. C. 1945. The control of contaminants in penicillin 

 fermentations by antiseptic chemicals. Jour. Bact. 50: 505-516. 



AND Frazier, W. C. 1945. The effect of corn steep liquor ash on penicillin 



production. Science 102: 617-618. 



