220 CARNEGIE INSTITUTION OF WASHINGTON. 



being repaid. The presentation to scientific and academic circles of informa- 

 tion regarding the work of the Carnegie Institution of Washington in gen- 

 eral was most profitable. 



During the absence of the Director on foreign tour, the Laboratory was 

 successfully directed by Dr. Thorne M. Carpenter, who was appointed by 

 President Merriam as Acting Director. 



COOPERATING AND VISITING INVESTIGATORS. 



Dr. Elliott P. JosHn and his assistants have been occupied in reading and 

 revising the proof of the third diabetic monograph, which has just been issued. 



Professor E. G. Ritzman, of the Department of Animal Nutrition of the 

 University of New Hampshire, has, in accordance with a liberal arrangement 

 made by President R. D. Hetzel and Director John C. Kendall, devoted the 

 greater part of his time to the conduct of metabolism studies with large 

 domestic animals. A respiration chamber has been employed for these 

 studies in a separate building provided by the authorities of the University, 

 thus in effect establishing an institute of animal nutrition. 



Miss Grace MacLeod, of the Department of Nutrition, Teachers College, 

 Columbia University, New York, with the hearty support of Professors 

 Henry C. Sherman and Mary Swartz Rose, has continued the investigation 

 of the metabohsm of the white rat. 



Many foreign investigators have visited the Nutrition Laboratory, among 

 them a commission from the University of Strasburg, which included the 

 dean of the Faculty of Medicine, Professor Georges Weiss, and Professors 

 Maurice Nicloux and Leon Blum. We were visited also by Professor and Mrs. 

 August Krogh, of Copenhagen, and Professors H. J. Hamburger, of Gronin- 

 gen; Leon Asher, of Berne; I. P. Pawlow, of Petrograd; Bela Schick, of 

 Vienna; O. Meyerhof, of Kiel; A. Samoiloff, of Kasan; Drs. G. B. Fleming, 

 of Glasgow; F. G. Banting, of Toronto; Paul Roth, of Battle Creek; and 

 S. Hata, of Tokyo. 



Mrs. C. G. Benedict worked for several months as a volunteer associate 

 in the Laboratory and during this time developed a new form of respiration 

 apparatus which has created great interest in medical centers. 



INVESTIGATIONS IN PROGRESS. 



Standardization of respiratory exchange apparatus. — Continuing his critical 

 examination of methods of studying the respiratory exchange, Dr. Carpenter 

 has tested the accuracy of several types of apparatus for the determination 

 of the respiratory exchange, particularly the oxygen absorption. The 

 apparatus used was a mechanico-chemical testing device which comprised 

 a special lamp, a hand spirometer, and a special burette for alcohol or acetone. 

 A study was made of the Benedict and Collins portable respiration apparatus, 

 the Roth modification, a Benedict apparatus with outside blower, and the 

 Benedict student respiration apparatus. A report of the results is now in 

 press. The possibility of applying the Benedict universal respiration appa- 

 ratus to the determination of the respiratory quotient in continuous periods 

 has been studied, as well as the gasometer method of determining the respira- 

 tory quotient. These tests have all been made by Mr. E. L. Fox and Mr. 

 E. S. Mills. 



Composition of the urine of steers. — The studies of the composition of steers' 

 urine collected in connection with the metabolism experiments at the Agri- 



