CLARK: CYTOLOGY OF CARCINOMA. 231 



Cell Nest 12, XLL 



Direct D 2 2.0 2 



Indirect D 2 3 4.6 . 5 371 



Cell Nest 12, XLII. 



Direct D 1 1 . . 2 . 4.2 4 



Indirect D. 4 2 3. . 1 . 2.3 . 10 421 



No. of cells. Direct divisions. Indirect divisions. 



12,228 81 285 



Percentage of cells in divisions 2.99 



" of cells in direct divisions 6 



" of cells in indirect divisions 2.3 



" of divisions which are direct 22.1 



" of divisions which are indirect 77.9 



Table of all the nests counted, showing percentage of cells 

 in division, percentage of cells in direct division, and percent- 

 age of cells in indirect division : 



The writer of this paper wishes here to acknowledge his in- 

 debtedness to Doctor McClung, whose kind suggestions made 

 this work possible, and to Doctor M. T. Sudler for the material 

 and clinical data upon which this study is based. 



CONCLUSIONS. 



1. The percentage of cells in division shows no relation to 

 the percentage of amitoses or mitoses. 



2. The percentage of mitoses is high in small non-necrotic 

 nests. 



3. The percentage of amitoses is high in large necrotic nests, 

 indicating that it is the division associated with degeneration. 



4. Amitosis is the form of division occurring in the necrotic 

 area. 



5. The rate of division in the various nests is inconstant. 



6. The directly dividing cells lie nearer the center of the cell 



3-Univ. Sci. Bull.. Vol. V. No. 12. 



