246 THE UNIVERSITY SCIENCE BULLETIN. 



Streptococcus pyogenes bears to Streptococcus mitis. They mention 

 it as occurring in cases of scarlatinal and other forms of sore 

 throat. It produces a flocculent deposit in broth, clots milk, re- 

 duces neutral red, forms acid in saccharose, lactose, and raffinose. 



The enterococcus of Thiercelin, Escherich, Beeson^ and others 

 is a pleomorphic streptococcus that varies from the streptococcus 

 of Gordon in its growth in broth, milk and on agar. 



The object of this paper is to report upon a pleomorphic strain 

 of the streptococcus isolated from chronically enlarged cervical 

 lymph glands of a patient otherwise apparently in good health, 

 and to compare this with eight other more or less markedl^^ pleo- 

 morphic streptococci isolated from five cases of tonsilitis, two 

 cases ot bronchitis, and one case of infection on back of hand and 

 with Streptococcus pyogenes and Bacillus diphtheria. The basis of 

 comparison is upon morphology, staining reactions, cultural char- 

 acteristics, action on carbohydrates according to Andrew's and 

 Horder's classification, and complement fixation tests. 



In November, 1912, a local physician requested a bacteriological 

 examination of material from the cervical lymph glands of a 

 patient with the following history: Male, age 26; had noticed 

 twenty-six months previously the enlargement of the cervical 

 lymph glands on the right side of the neck. Nineteen months 

 later he attended a hospital clinic, drainage was established, and 

 the case observed at intervals by the attending physician for seven 

 months. During this time the glands continued to enlarge. At 

 the end of seven months the patient went to his family physician, 

 who suggested the bacteriological examination. No acid-fast 

 organisms were found, but a pure culture of a marked pleomorphic 

 streptococcus was obtained both from the glands and from the 

 tonsils. At this time the glands on both sides were involved; the 

 axillary and inguinal lymph glands were shotty. The physician 

 advised a tonsillectomy, but the patient wanted a vaccine. Ac- 

 cordingly a vaccine was prepared. Three weeks after the admin- 

 istration of the first dose the swelling had disappeared and the 

 patient was discharged. Three months afterward there seemed 

 to be the beginning of a recurrence, a tonsillectomy was performed, 

 and the patient has remained well to date. 



The organism isolated had the following characteristics, which, 

 in so far as morphology, staining reactions and general cultural 

 characteristics are concerned, seemed to be identical with those of 

 Streptococcus scarlatina of Klein and Gordon and the Streptococcus 



