316 



MEDICAL MYCOLOGY 



be specifically identical with 5. schenckii. This organism com- 

 monly enters through some minor injury, such as a barberry, rose, 

 or bramble puncture. Evidence also points to inoculation from 

 splinters or into abrasions incurred in the work of clearing land. 

 An ulcerative lesion that fails to heal develops. Gradually subcu- 

 taneous abscesses form that spread along the lymphatics, dissemi- 

 nation apparently being hematogenous. Once the disease becomes 



Fig. 70. Sporotrichum schenckii. (Adapted from Moore.) A. Germinat- 

 ing spores. B. Yeast-like spores. C. Aleurospores laterally formed in cul- 

 ture. D. Terminally formed spores that may become chlamydospore-like. 

 E. Both intercalary and terminal chlamydospores may form in culture. 



F. Conidia formed abundantly. 



systemic, various organs, muscles, bones, lungs, joints, and other 

 tissues, including the brain and viscera, become involved. 



Sporotrichosis may occur spontaneously in horses, dogs, cats 

 and rabbits. Attention was called by du Toit (1942) to the occur- 

 rence of 5. beitrmanni on wood, mud, and other materials in a 

 mine in the Transvaal, where an outbreak of sporotrichosis in- 

 volved 650 among 2500 native miners. The organism was intro- 

 duced by a worker. Sterilized wood and mud constituted good 

 substrata for the cultivation of S. beurmanni. 



On agar the fungus forms white colonies that may become 

 brownish with age. Temperatures within the range 30° to 38° C 

 are optimum. The hyphae are much branched, and chlamydo- 

 spores appear on media poor in nutrients. Conidiophores are not 



