292 Seventeenth Annual Report of the 



cater, therefore, is largely cine to the cooking, and, according to 

 the thoroughness of the cooking, the meat is free from danger to 

 the consumer. 



SYMPTOMS IN MAN 



These vary even more than in the lower animals, chiefly for 

 the reason that man is usually infected from eating or drinking, 

 so that the disease often makes its eruption on the internal organs, 

 especially the stomach and bowels, instead of the mouth, mammary 

 glands and feet. Even in man, however, the eruption shows a 

 strong tendency to the three parts just named, the mouth rarely 

 escaping, while the fingers occasionally, and the breasts exception- 

 ally suffer. 



When the hands are used in milking they are especially liable 

 to infection and eruption and, on the other hand, the mouth is 

 always exposed to direct infection when the germ enters in food 

 as in uncooked milk, butter or cheese. But the tendency of the 

 disease to localize itself on the internal organs favors the develop- 

 ment of a more marked febrile reaction, and this, with the greater 

 tendency of man to nausea, often gives the affection a very pecu- 

 liar and remarkable aspect. 



Incubation is about two days (Hertwig's case), but this may be 

 materially prolonged as in cattle. 



In mild cases there is dullness, langour, pains in the back 

 and limbs, diminished appetite or none, sometimes giddiness, 

 nausea, and a sense of weakness. Chills are the rule, but they 

 are slight in mild cases; there may be merely a feeling of 

 coldness with goose-skin; there may be violent trembling, or 

 active shivering and clammy coldness of feet and hands. Even 

 during the chill, the temperature of the body is abnormally 

 high, as shown by placing the clinical thermometer in the armpit, 

 or under the tongue. This may vary from 100° to 102° F. in 

 adults, or 102° to 103° E. in children, and upward, reaching 105° 

 or 106° F. in grave cases. The chill is followed by the reaction, 

 with a hot, burning skin, especially on the brow, palms and solo-, 

 but extending more or less to the entire surface of the body. In 

 grave cases the chills and hot stage may alternate with each other 

 again and again, the intensity and persistency bearing a relation 

 to the gravity of the case. 



Usually on the second day of the illness the eruption of the 



