Commissioner of Agriculture. 241 



test. This was done, and the animal gave a typical reaction 

 and was condemned, appraised and killed. The post mortem 

 confirmed the diagnosis. I made inquiries of the neighbors rela- 

 tive to any other cases and they stated that they knew of this 

 horse working with various horses, but never knew of any 

 suspicious cases in any of the horses with which it had worked. 

 I called upon the health officer, a doctor, who stated about 

 the same as above. He also stated that he had used this 

 same gray horse with his own horses during his spring's 

 work, and that lately he noticed a discharge from the 

 nostrils of one. I made an examination and found both of 

 his horses suffering from glanders and they were immedi- 

 ately killed. The hotel proprietor informed me that about 

 two years ago this man's son purchased this horse as 

 having glanders. This old gray horse had been owned for 

 several years by different persons in the adjoining towns, 

 yet no infection had been noticed until this year, when 

 five horses contracted the disease. One died, the other four 

 were killed upon the mallein test and the post-mortem confirmed 

 the diagnosis. Glanders is essentially an equine disease and 

 affects donkeys, mules and jennets as well as horses. It can be 

 transmitted from the horse to many other animals, including 

 man, either by direct or indirect infection. The following 

 animals are susceptible according to the order in which they are 

 named: Field mice and guinea pigs, cat tribes (including lion 

 and tiger), dogs, goats, rabbits and sheep. Pigs and pigeons are 

 scarcely at all susceptible. Cattle seem to be immune, and in 

 several instances glandered horses have been put into cattle 

 sheds and never has there been a well authenticated case of 

 glanders in a bovine recorded. House mice, white mice, rats, 

 domestic fowls and linnets are also immune. 



Pathogenesis. 



Glanders can be transmitted directly or indirectly through 

 different medias, such as harness, clothing, pails, stables, water- 

 lfi 



