378 Report of the Department of Chemistry of the 



For analysis it was dried at 100° in vacuum over phosphorus 

 pentoxide but it did not lose in weight. 



0.1550 gram subst. gave 0.0749 gm. H 2 and 0.1566 gm. C0 2 . 



0.0766 gram subst. gave 0.0325 gm. Mg 2 P 2 7 . 



Found: C = 27.55; H = 5.40; P = 11.82 per ct. 



For inosite monophosphate, C 6 Hi 3 9 P = 260. 



Calculated: C = 27.69; H = 5.00; P = 11.92 per ct. 



Titrated against barium hydroxide, using phenolphthalein as 

 indicator, it forms the neutral barium salt, C 6 H n 09P Ba. 



0.1985 gram subst. required 7.6 c.c. £ Ba(OH) 2 . 



For CeHnOgP Ba, calculated: 7.6 c.c. £ Ba(OH) 2 . 



PROPERTIES OF INOSITE MONOPHOSPHATE. 



The acid is very soluble in water. The aqueous solution shows 

 a strong acid reaction to litmus and it has a sharp, somewhat astrin- 

 gent, acid taste. It is insoluble in alcohol, ether and the other 

 usual organic solvents. 



Its aqueous solution gives no precipitate with barium hydroxide 

 or with calcium or barium chloride; ammonia produces no precipitate 

 in these solutions but the addition of alcohol causes white amorphous 

 precipitates. Silver nitrate produces no precipitate even in a solution 

 neutralized with ammonia. When alcohol is added to the solution 

 containing silver nitrate a white amorphous precipitate is produced 

 which dissolves on warming; on cooling the silver salt separates 

 in small, round crystal aggregates. It gives no precipitate with 

 ferric chloride or mercuric chloride nor with copper sulphate. In 

 the cold no precipitate is produced with copper acetate, but on 

 warming this solution a bluish-white precipitate separates which 

 again dissolves completely on cooling. 



With excess of lead acetate a white, heavy amorphous precipitate 

 is formed which is but slightly soluble in dilute acetic acid, but readily 

 soluble in dilute hydrochloric or nitric acid. Ammonium molybdate 

 produces no precipitate in either dilute or concentrated aqueous 

 solutions. ■ 



The acid crystallizes without water of crystallization from either 

 water or dilute alcohol. 



The aqueous solution of inosite monophosphate does not precipi- 

 tate egg albumen, differing in this respect from phytic acid. 



CLEAVAGE OF INOSITE MONOPHOSPHATE INTO INOSITE AND PHOS- 

 PHORIC ACID. 



I. ACID HYDROLYSIS. 



The acid, 0.35 gram, was heated in a sealed tube with 15 c.c. of 

 3 per ct. sulphuric acid to 120°-125° for about 3| hours. After 

 cooling, the liquid was of a pale straw color. The sulphuric and 

 phosphoric acids were precipitated with barium hydroxide and the 



