18 THE BUREAU OF SCIENCE 



toxin, and since April the demand for the antitoxin has exceeded 

 the supply. A number of inquiries relative to the Pasteur treat- 

 ment were received, and an opportunity was given to correct 

 several misunderstandings as to the nature of this treatment and 

 its application, which may account for the increase in the num- 

 ber of cases treated during the year. 



INVESTIGATION 



The articles published in the Philippine Journal of Science 

 are given on pages 45, 46. Other investigations have been made, 

 but the reports are not yet published. 



Cholera. — The investigation as to the mutability of the cholera 

 vibrio has been continued by Doctor Schobl at the New York 

 Quarantine Station. 



Malaria. — Doctor Barber and his assistants completed their 

 study of malaria in the Philippines and conducted a survey as to 

 the distribution of the commoner forms of anopheline mosquitoes 

 and the distribution of malaria. 



Leprosy. — The studies in the etiology and bacteriology of le- 

 prosy ar-e still being continued. Experimental work with ani- 

 mals in two instances has given very promising results. The 

 investigations of chaulmoogra oil with a view to obtaining an 

 active principle or an allied body, begun last year in cooperation 

 with the organic chemists, are being continued, and treatment 

 with the various fractions and products that have been obtained 

 from the crude oil are now being made available to patients at 

 the Culion Leper Colony. 



Plague. — The routine work of the examination of rats has been 

 continued. But one case of rat plague has been discovered. 



Pathology. — An important monograph on the pathology of 

 plague was completed during the year. 



Sanitary Health Commissions. — For many years it has been 

 the policy in the conduct of the biological work of the Bureau of 

 Science to send men to various provinces outside of Manila, when 

 opportunity presented itself, for the study of disease. In 1909 

 an extensive expedition for the purpose of carrying on a complete 

 medical survej^ in a typical provincial town was organized by the 

 Bureau of Science and the Bureau of Health of the Philippine 

 Government. The information obtained was thought to be typ- 

 ical of a Filipino town under normal conditions, and the results 

 have been very helpful in the work of sanitation. During recent 

 years, owing to the increases in routine work and the reduction 

 of staff, less of this work has been done, whereas for the best 

 interest of the Filipino people the work should have been ex- 



