TERATOGENESIS, CONGENITAL MALFORMATIONS (see also 51,55,70,71,98) 

 Monographs 



48. 



T.V.N. PERSAUD. 1979. TERATOGENESIS, experimental aspects and clinical implica- 

 tions 



Fischer, Jena. Exp. Pathol, suppl.4. 128 pp., 51 figs., 23 tabs., subject in- 

 dex. M.45.00 (paper) 



Contents (abridged) : Regulatory processes during normal and abnormal devel- 

 opment; General mechanisms and principles of teratogenesis; Environmental 

 teratogens; Evaluation of teratogenic risks 



This is a selective but very useful survey of the subject with emphasis on 

 current concepts, recent research and contemporary experimental techniques. 

 The account is clearly organised and much useful recent information is brought 

 together into tables and diagrams. 



The chapter on environmental teratogens has separate sections on laboratory 

 studies, human teratogenesis, and the relevance of the former to the latter. 

 The last chapter has separate sections on the use of the chick embryo and of 

 in vitro test systems. 



The volume is adequately illustrated. The bibliography of some 900 titles 

 is up to date until 1976 and does not restrict itself to Anglo-Saxon publica- 

 tions. 



Symposium reports 



49. 



N.C.MYRIANTHOPOULOS and D.BERGSMA, eds. 1979. RECENT ADVANCES IN THE DEVELOP- 

 MENTAL BIOLOGY OF CENTRAL NERVOUS SYSTEM MALFORMATIONS 



Liss, New York. Birth Defects: Original Article Series, vol. XV, 3. XIV, 130 pp. 

 45 figs., 15 tabs., subject index. $ 16.00, Dfl.48.00 



available in Europe and the Middle East from European Book Service, Weesp, 

 Netherlands 



This symposium was held on the occasion of the 11th World Congress of Neu- 

 rology (time not specified in the book). The book contains seven competent, 

 medium-length reviews of recent (and some older) work, as well as an intro- 

 duction and synthesis by the first editor. 



We only single out here those contributions that are of particular interest 

 to our readers: Errors in differentiation of the CNS (by Kallen) ; Scanning 

 electron microscope studies of CNS development (by Waterman) ; Surface mole- 

 cules involved in interactions among neural cells during development (by 

 Edelman's group); Are there human analogs of the mouse T locus in CNS malfor- 

 mations? (by F.Jacob's group) . Other papers deal with the epidemiology, 

 etiology and prevention of CNS malformations. The references cited go until 

 1976/77. 



The book is well produced and illustrated. 



50. 



R.L.SUMMITT and D.BERGSMA, eds. 1978. SEX DIFFERENTIATION AND CHROMOSOMAL 



ABNORMALITIES 



Liss, New York. Birth Defects: Orig. Article Series, vol.14, no,6C. 



XX, 434 pp., 160 figs., 67 tabs., subject index. $ 44,00, Dfl. 132.00 



available in Europe and the Middle East from European Book Service, Weesp, 



Netherlands 



This report of a 1977 symposium is mainly of interest to clinicians. We 

 only consider section I: Selected abnormalities of sex differentiation. This 



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