CELLULAR DEVELOPMENTAL BIOLOGY (incl. cell culture, cytochemistry) (see also 



30,37,52,56,57,58,59,69,72) 



Symposium reports 



75. 



B.CLARKSON, P.A.MARKS and J. E. TILL, eds. 1978. DIFFERENTIATION OF NORMAL AND 



NEOPLASTIC HEMATOPOIETIC CELLS. 2 vols. 



Cold Spring Harbor Lab., Cold Spring Harbor, N.Y. Cold Spring Harbor Conf. on 



Cell Proliferation vol.5 A & B. XVI, XIV, 994 pp., 272 figs., 4 pis., 191 tabs., 



index to contrib. and authors, subject index. $ 80.00 (set) 



Contents: 1. Ontogeny of hematopoietic development and stem cells (9 pa- 

 pers), 2. Erythrocyte differentiation and regulation (13), 3. Granulocyte 

 and monocyte differentiation and regulation (7), 4. Lymphocyte differentia- 

 tion and regulation (7) , 5. Viruses - transformation and differentiation 

 (11), 6. Cytogenetics and expression of cell-surface antigens (3), 7. Mar- 

 row architecture and microenvironment (3) , 8. Clinical-pathological rela- 

 tionships and differentiation of human hematopoietic tumors (9) 



This is vol.5 of a well-known series of conferences. This one was apparent- 

 ly held some time during 1977. The majority of contributors were North-Amer- 

 icans but many other countries were represented. Most of the 62 papers are 

 brief to medium-length research reports or mixtures of review and research 

 material. The discussions are not recorded. All sections except nrs.6 and 7 

 have brief introductions by the session chairmen (Till, Marks, Moore, Cantor 

 and Boyse, Baltimore, Lennert) . 



The volumes are well produced and illustrated. 



76. 



A. S.G.CURTIS, ed. 1978. CELL-CELL RECOGNITION 



Cambridge Univ. Press, Cambridge, etc. Symposia of the Soc. for Exp. Biol. 



No. 32. VIII, 478 pp., 63 figs., 36 pis., 59 tabs., author and subject indexes. 



£ 20.00 



Contributors: Burger, Crandall, Curtis, Dales, De Sousa, Ford, Garrod, 



Greaves, Heslop-Harrison, Hoover, Horder, Katz , Newell, Pierce, Rees, 



Steinberg, Wiese, Yeoman 



This excellent report of a symposium held in September 1977 is a must for 

 all those working in the field themselves. Large parts of it I would even 

 consider required reading for almost every developmental biologist. This 

 particularly holds for three lengthy reviews on the three main competing 

 theories of cell recognition: those of specific adhesion (Burger et at.), 

 differential adhesion (Steinberg) , and interaction modulation (formerly 

 called the "morphogen" theory) (Curtis) . Also extremely valuable is the ex- 

 tensive review by Horder and Martin (85 pp.) on the formation of nerve cell 

 connections, in which they defend the thesis (based mostly on the results of 

 optic nerve regeneration in goldfish) that the major determinants of the de- 

 velopment of the nervous system are mechanical forces rather than chemical 

 specificity. 



Ten of the contributing authors or groups are British, seven American, and 

 one Swiss. The longer of the 18 contributions are reviews, the shorter ones 

 progress reports, but all are authoritative, up to date and well written. 

 The articles are adequately cross-referenced. The range of recognition phe- 

 nomena covered includes those in plants, slime moulds, metazoan invertebrates, 

 vertebrates, and lymphocytic and related systems (cellular immunology). The 

 only subject that embryologists will find missing is fertilisation in animals. 

 The book is well produced and very well illustrated. 



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