131 [ern 
@ series of vesicating applications, the joint is re- 
stored to its freedom and anchylosis prevented. 
Numerous other surgical benefits are obtained 
from these remedies, which I need not here detail. 
They are contra-indicated by idiosyncracies, 
which render them productive of great distress, 
by painful strangury, great constitutional irrita- 
tion, heat of body, insatiable thirst, spasm and 
convulsions. In peculiarly sensitive tempera- 
ments, the strangury is excruciating, and termi- 
nates in bloody urine, particularly when the blisters 
are applied contiguous to the urinary organs; to 
parts recently shaved ; and if kept on an undue time 
after the vesication is raised. 'Uhey are also contra- 
indicated in cases of great debility, with tendency 
to mortification: as low stages of petechial fever, in 
which Ihave in the army recruit service, seen 
gangrene and other distressing occurrences hap- 
pen, from their use under my own direction. In 
confluent small-pox, malignant measles, and other 
similar diseases, they have proved very trouble- 
some to heal, and have even prodaced gangrene 
of the part. 
To relieve strangury it has been proposed to 
unite camphor with the blister or annoint the part 
to which it is to be applied with camphorated oil. 
But there are many instances in which camphor 
itself has induced strangury. Uva-ursi simulta- 
neously administered with the application of the 
blister, was strongly recommended by the late Dr. 
Barton, to obviate this distressing affection. It 
certainly is a practice which often prevents the 
evil. yet it must be remembered there are cases 
in which blisters may be proper, while the pro- 
phylactic is inadmissable Diluent drinks have 
Seen - prescribed with this view: such as milk 
o 
